HitPredict

Interactor 1: STX1B (P61266)
Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2)
Gene: STX1B

Interactor 2: SNAB (Q9H115)
Beta-soluble NSF attachment protein (SNAP-beta) (N-ethylmaleimide-sensitive factor attachment protein beta)
Gene: NAPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SNAP~SNARE, SNAP~Syntaxin
Common GO terms	GO:0006886 - intracellular protein transport GO:0010807 - regulation of synaptic vesicle priming
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 288 Hs			1 298
+	Hs
		746223 STX2_HUMAN (1-287): 3.91e-80: 245: 64.81		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Hs
		1159633 STX1A_HUMAN (1-286): 1.75e-76: 236: 81.88		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Mm
		204935 STX1A_MOUSE (1-287): 1.15e-78: 241: 82.29		SNAA_MOUSE (1-293): 4.85e-109: 319: 83.62
+	Rn
		746106 STX1A_RAT (1-287): 1.61e-78: 241: 81.94		SNAA_RAT (1-293): 2.21e-108: 318: 82.94
+	Hs
		933012 STX1A_HUMAN (1-286): 1.75e-76: 236: 81.88		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		1087275 STX4_HUMAN (1-286): 5.02e-61: 197: 46.28		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Dm
		1171600 STX1A_DROME (2-282): 4.04e-72: 225: 69.01		SNAP_DROME (5-292): 1.03e-103: 306: 62.15
+	Hs
		1100716 STX3_HUMAN (1-288): 7.89e-59: 191: 59.79		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Hs
		1430777 X5D7S1_HUMAN (1-285): 2.41e-59: 191: 68.53		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Hs
		932999 STX4_HUMAN (1-286): 5.02e-61: 197: 46.28		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		286724 STX11_HUMAN (1-273): 4.01e-53: 176: 33.57		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Hs
		933004 STX3_HUMAN (1-288): 7.89e-59: 191: 59.79		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		160914 STX16_HUMAN (27-263): 2.58e-50: 170: 21.99		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Hs
		286636 STX11_HUMAN (1-273): 4.01e-53: 176: 33.57		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		160876 STX16_HUMAN (27-263): 2.58e-50: 170: 21.99		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Dm
		1174532 STX1A_DROME (2-282): 4.04e-72: 225: 69.01		Q9U6R9_DROME (4-265): 3.28e-59: 193: 19.70
+	Hs
		1100712 STX3_HUMAN (1-288): 7.89e-59: 191: 59.79		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Dm
		1174540 STX1A_DROME (2-282): 4.04e-72: 225: 69.01		Q9VH25_DROME (42-265): 8.65e-52: 173: 19.03
+	Hs
		286715 STX11_HUMAN (1-273): 4.01e-53: 176: 33.57		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Hs
		160913 STX16_HUMAN (27-263): 2.58e-50: 170: 21.99		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30