HitPredict

Interactor 1: MRP4 (O15439)
ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4)
Gene: ABCC4

Interactor 2: S1PR3 (Q99500)
Sphingosine 1-phosphate receptor 3 (S1P receptor 3) (S1P3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor Edg-3) (S1P receptor Edg-3)
Gene: S1PR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1325 Hs			1 378
+	Hs
		190582 MRP4_HUMAN (1-1325): 0: 1079: 100.00		S1PR4_HUMAN (15-352): 1.92e-81: 255: 41.06
+	Hs
		190592 MRP4_HUMAN (1-1325): 0: 1079: 100.00		GPR12_HUMAN (42-327): 1.29e-65: 213: 26.62
+	Hs
		190625 MRP4_HUMAN (1-1325): 0: 1079: 100.00		LPAR1_HUMAN (15-334): 1.2e-64: 211: 35.69
+	Hs
		190591 MRP4_HUMAN (1-1325): 0: 1079: 100.00		OPRX_HUMAN (31-349): 4.4e-64: 210: 15.24
+	Hs
		351937 MRP2_HUMAN (611-1294): 2.2e-55: 214: 15.73		S1PR4_HUMAN (15-352): 1.92e-81: 255: 41.06
+	Hs
		753840 MRP1_HUMAN (621-1305): 1.89e-58: 224: 14.62		S1PR3_HUMAN (1-378): 2.23e-75: 239: 100.00
+	Hs
		753832 MRP1_HUMAN (621-1305): 1.89e-58: 224: 14.62		LPAR1_HUMAN (15-334): 1.2e-64: 211: 35.69