Protein: MRP2
ATP-binding cassette sub-family C member 2 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multidrug resistance protein) (Canalicular multispecific organic anion transporter 1) (Multidrug resistance-associated protein 2)

Gene: MRP2, ABCC2
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q92887

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006805 - xenobiotic metabolic process
GO:0006855 - xenobiotic transmembrane transport
GO:0008514 - organic anion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

162852

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

2

9

Small-scale

0.602

High

1212230

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

9

Small-scale

0.594

High

1369920

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.586

High

626312

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.573

High

1369924

UBQL1
Ubiquilin-1

1

1

High-throughput

0.541

High

125554

LEG9
Galectin-9

1

13

High-throughput

0.536

High

166004

FFAR1
Free fatty acid receptor 1

1

5

High-throughput

0.536

High

351937

S1PR4
Sphingosine 1-phosphate receptor 4

1

7

High-throughput

0.536

High

609768

LEG3
Galectin-3

1

13

High-throughput

0.536

High

1233115

LAIR1
Leukocyte-associated immunoglobulin-like receptor 1

1

1

High-throughput

0.536

High

1369918

OPALI
Opalin

1

1

High-throughput

0.536

High

1369922

CP26B
Cytochrome P450 26B1

1

1

High-throughput

0.536

High

1369925

CCG2
Voltage-dependent calcium channel gamma-2 subunit

1

0

High-throughput

0.513

High

1369926

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

761800

HSP74
Heat shock 70 kDa protein 4

1

2

Small-scale

0.501

High

767480

RADI
Radixin

1

4

Small-scale

0.501

High

1288998

NHRF4
Na(+)/H(+) exchange regulatory cofactor NHE-RF4

1

9

Small-scale

0.501

High

1126333

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

2

High-throughput

0.489

High

1369919

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

2

High-throughput

0.481

High

375806

RASK
GTPase KRas

1

15

High-throughput

0.479

High

1026160

CLH1
Clathrin heavy chain 1

1

3

Small-scale

0.479

High

1288751

KTN1
Kinectin

1

1

High-throughput

0.479

High

172160

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

1

High-throughput

0.470

High

1369916

AP2M1
AP-2 complex subunit mu

1

0

Small-scale

0.458

High

1141843

EEA1
Early endosome antigen 1

1

1

High-throughput

0.437

High

1369923

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

171809

AZIN1
Antizyme inhibitor 1

1

0

High-throughput

0.282

High

219343

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.279

Low

1369917

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.279

Low

1369921

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1108646

TBB3
Tubulin beta-3 chain

1

0

Small-scale

0.261

Low

1337532

MCPH1
Microcephalin

1

0

High-throughput

0.251

Low

872601

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

1129167

IRF3
Interferon regulatory factor 3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025