Protein: GPR12
G-protein coupled receptor 12

Gene: GPR12
Organism: Homo sapiens
Interactions: 124
UniProt ID: P47775

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006874 - intracellular calcium ion homeostasis
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

755530

TTK
Dual specificity protein kinase TTK

1

4

High-throughput

0.691

High

867616

MTR1L
Melatonin-related receptor

1

18

High-throughput

0.691

High

867639

WDFY3
WD repeat and FYVE domain-containing protein 3

1

2

High-throughput

0.691

High

296908

DGAT1
Diacylglycerol O-acyltransferase 1

2

2

High-throughput

0.601

High

867612

TAP1
Antigen peptide transporter 1

2

8

High-throughput

0.549

High

867613

TAP2
Antigen peptide transporter 2

2

8

High-throughput

0.549

High

65450

TLCD2
TLC domain-containing protein 2

1

1

High-throughput

0.536

High

178618

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

2

High-throughput

0.536

High

249443

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

3

High-throughput

0.536

High

256004

S19A2
Thiamine transporter 1

1

3

High-throughput

0.536

High

332208

UCP5
Brain mitochondrial carrier protein 1

1

11

High-throughput

0.536

High

562785

CY24A
Cytochrome b-245 light chain

1

2

High-throughput

0.536

High

565577

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

20

High-throughput

0.536

High

603881

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.536

High

755332

ABCD1
ATP-binding cassette sub-family D member 1

1

11

High-throughput

0.536

High

867606

CTR2
Cationic amino acid transporter 2

1

5

High-throughput

0.536

High

867608

AT12A
Potassium-transporting ATPase alpha chain 2

1

17

High-throughput

0.536

High

867610

TBA4A
Tubulin alpha-4A chain

1

7

High-throughput

0.536

High

867614

MTX1
Metaxin-1

1

5

High-throughput

0.536

High

867615

TBB3
Tubulin beta-3 chain

1

5

High-throughput

0.536

High

867618

STAR3
StAR-related lipid transfer protein 3

1

3

High-throughput

0.536

High

867625

MTX3
Metaxin-3

1

5

High-throughput

0.536

High

867626

MRP7
ATP-binding cassette sub-family C member 10

1

9

High-throughput

0.536

High

867629

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

8

High-throughput

0.536

High

867631

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

5

High-throughput

0.536

High

867638

MOT13
Monocarboxylate transporter 13

1

1

High-throughput

0.536

High

867644

T161B
Transmembrane protein 161B

1

2

High-throughput

0.536

High

867647

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

14

High-throughput

0.536

High

867648

S35G2
Solute carrier family 35 member G2

1

5

High-throughput

0.536

High

867650

SPPL3
Signal peptide peptidase-like 3

1

2

High-throughput

0.536

High

867654

S20A1
Sodium-dependent phosphate transporter 1

1

1

High-throughput

0.536

High

867656

CTR3
Cationic amino acid transporter 3

1

4

High-throughput

0.536

High

867660

PAQR1
Adiponectin receptor protein 1

1

3

High-throughput

0.536

High

867663

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

8

High-throughput

0.536

High

867666

PANX1
Pannexin-1

1

1

High-throughput

0.536

High

867669

S29A1
Equilibrative nucleoside transporter 1

1

2

High-throughput

0.536

High

867670

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

5

High-throughput

0.536

High

867671

TBA1C
Tubulin alpha-1C chain

1

8

High-throughput

0.536

High

867673

NDC1
Nucleoporin NDC1

1

2

High-throughput

0.536

High

867691

CDYL
Chromodomain Y-like protein

1

2

High-throughput

0.536

High

867692

SC5A6
Sodium-dependent multivitamin transporter

1

3

High-throughput

0.536

High

867694

DAAM1
Disheveled-associated activator of morphogenesis 1

1

3

High-throughput

0.536

High

867605

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.513

High

867651

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.513

High

867661

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.513

High

867665

RBM14
RNA-binding protein 14

1

0

High-throughput

0.513

High

867667

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.513

High

867668

CDC6
Cell division control protein 6 homolog

1

0

High-throughput

0.513

High

867682

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.513

High

421692

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

122599

UBXN8
UBX domain-containing protein 8

1

1

High-throughput

0.489

High

173678

BTAF1
TATA-binding protein-associated factor 172

1

6

High-throughput

0.489

High

178918

SCAM2
Secretory carrier-associated membrane protein 2

1

9

High-throughput

0.489

High

223710

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

3

High-throughput

0.489

High

226474

SNG3
Synaptogyrin-3

1

6

High-throughput

0.489

High

228070

PM34
Peroxisomal membrane protein PMP34

1

11

High-throughput

0.489

High

295910

SC5D
Lathosterol oxidase

1

7

High-throughput

0.489

High

431395

AT5G1
ATP synthase F(0) complex subunit C1, mitochondrial

1

1

High-throughput

0.489

High

593577

GDC
Solute carrier family 25 member 16

1

10

High-throughput

0.489

High

867622

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

5

High-throughput

0.489

High

867623

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

1

High-throughput

0.489

High

867628

TM164
Transmembrane protein 164

1

2

High-throughput

0.489

High

867630

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

3

High-throughput

0.489

High

867632

ATLA3
Atlastin-3

1

4

High-throughput

0.489

High

867636

CERS6
Ceramide synthase 6

1

14

High-throughput

0.489

High

867640

S35F6
Solute carrier family 35 member F6

1

3

High-throughput

0.489

High

867641

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

1

High-throughput

0.489

High

867642

F241A
Uncharacterized protein FAM241A

1

3

High-throughput

0.489

High

867643

MFSD9
Major facilitator superfamily domain-containing protein 9

1

6

High-throughput

0.489

High

867652

SFXN5
Sideroflexin-5

1

1

High-throughput

0.489

High

867653

CHPT1
Cholinephosphotransferase 1

1

2

High-throughput

0.489

High

867657

CDS1
Phosphatidate cytidylyltransferase 1

1

1

High-throughput

0.489

High

867659

MFRN2
Mitoferrin-2

1

12

High-throughput

0.489

High

867664

VMA22
Vacuolar ATPase assembly protein VMA22

1

1

High-throughput

0.489

High

867677

ELOV4
Very long chain fatty acid elongase 4

1

4

High-throughput

0.489

High

867679

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

2

High-throughput

0.489

High

867684

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

3

High-throughput

0.489

High

867685

TM242
Transmembrane protein 242

1

1

High-throughput

0.489

High

867686

COX16
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial

1

1

High-throughput

0.489

High

867687

ORML1
ORM1-like protein 1

1

1

High-throughput

0.489

High

867688

MTFP1
Mitochondrial fission process protein 1

1

3

High-throughput

0.489

High

867690

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

2

High-throughput

0.489

High

867693

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

5

High-throughput

0.489

High

867695

PEX16
Peroxisomal membrane protein PEX16

1

2

High-throughput

0.489

High

867697

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

4

High-throughput

0.489

High

867609

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

Small-scale

0.480

High

190592

MRP4
ATP-binding cassette sub-family C member 4

1

7

High-throughput

0.445

High

867604

PSN1
Presenilin-1

1

2

High-throughput

0.445

High

867607

SC5A3
Sodium/myo-inositol cotransporter

1

3

High-throughput

0.445

High

867620

MSMO1
Methylsterol monooxygenase 1

1

7

High-throughput

0.445

High

867646

RAI3
Retinoic acid-induced protein 3

1

13

High-throughput

0.445

High

867676

S12A9
Solute carrier family 12 member 9

1

7

High-throughput

0.445

High

867678

S38A1
Sodium-coupled neutral amino acid symporter 1

1

3

High-throughput

0.445

High

867689

XPO7
Exportin-7

1

20

High-throughput

0.445

High

867696

AGRG1
Adhesion G-protein coupled receptor G1

1

13

High-throughput

0.445

High

867698

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

13

High-throughput

0.445

High

506573

GPHRB
Golgi pH regulator B

1

7

High-throughput

0.437

High

867683

TM7S3
Transmembrane 7 superfamily member 3

1

0

High-throughput

0.426

High

85349

GPHRA
Golgi pH regulator A

1

7

High-throughput

0.407

High

166885

MGST3
Glutathione S-transferase 3, mitochondrial

1

2

High-throughput

0.407

High

350353

ABHGA
Phosphatidylserine lipase ABHD16A

1

6

High-throughput

0.407

High

664954

ERD21
ER lumen protein-retaining receptor 1

1

6

High-throughput

0.407

High

755466

ERD22
ER lumen protein-retaining receptor 2

1

6

High-throughput

0.407

High

867611

ATL3
ADAMTS-like protein 3

1

5

High-throughput

0.407

High

867617

ERG1
Squalene monooxygenase

1

1

High-throughput

0.407

High

867621

D19L1
Protein C-mannosyl-transferase DPY19L1

1

2

High-throughput

0.407

High

867624

PIGG
GPI ethanolamine phosphate transferase 2, catalytic subunit

1

8

High-throughput

0.407

High

867633

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

10

High-throughput

0.407

High

867634

MBOA5
Lysophospholipid acyltransferase 5

1

8

High-throughput

0.407

High

867635

HACD2
Very-long-chain

1

3

High-throughput

0.407

High

867637

TMTC3
Protein O-mannosyl-transferase TMTC3

1

2

High-throughput

0.407

High

867649

RDH11
Retinol dehydrogenase 11

1

1

High-throughput

0.407

High

867658

SCAM4
Secretory carrier-associated membrane protein 4

1

9

High-throughput

0.407

High

867662

RUSF1
RUS family member 1

1

2

High-throughput

0.407

High

867674

LMF2
Lipase maturation factor 2

1

1

High-throughput

0.407

High

867675

TMM70
Transmembrane protein 70, mitochondrial

1

1

High-throughput

0.407

High

867681

ARMT1
Damage-control phosphatase ARMT1

1

1

High-throughput

0.407

High

328231

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.279

Low

867619

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.279

Low

867627

MFS4B
Sodium-dependent glucose transporter 1

1

0

High-throughput

0.279

Low

867672

APOL2
Apolipoprotein L2

1

0

High-throughput

0.279

Low

867680

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

867645

TM104
Transmembrane protein 104

1

0

High-throughput

0.232

Low

867655

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025