HitPredict

Interactor 1: MAGB2 (O15479)
Melanoma-associated antigen B2 (Cancer/testis antigen 3.2) (CT3.2) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2 antigen) (MAGE-B2 antigen)
Gene: MAGEB2

Interactor 2: KMT2A (Q03164)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 319 Hs			1 3969
+	Hs
		848941 MAGAB_HUMAN (1-317): 7.82e-152: 434: 40.13		SUV92_HUMAN (3577-3969): 1.16e-84: 287: 17.94
+	Hs
		1155902 MAGD2_HUMAN (2-311): 1.22e-106: 325: 31.08		EZH2_HUMAN (3450-3951): 2.55e-103: 353: 18.39
+	Hs
		848726 MAGA9_HUMAN (1-317): 9e-133: 381: 38.05		ASH1L_HUMAN (3279-3968): 1.48e-72: 275: 15.75
+	Hs
		191826 MAGB2_HUMAN (1-319): 1.28e-130: 376: 100.00		ASH1L_HUMAN (3279-3968): 1.48e-72: 275: 15.75
+	Mm
		1231082 MAGD1_MOUSE (33-308): 6.64e-90: 286: 29.35		Q6AXH7_MOUSE (3450-3951): 3.07e-102: 349: 18.03
+	Hs
		1155956 MAGD1_HUMAN (60-308): 2.12e-87: 279: 31.33		EZH2_HUMAN (3450-3951): 2.55e-103: 353: 18.39
+	Hs
		191508 MAGB2_HUMAN (1-319): 1.28e-130: 376: 100.00		NSD2_HUMAN (3752-3968): 6.99e-60: 231: 27.23
+	Hs
		216352 MAGC1_HUMAN (111-316): 1.66e-42: 158: 46.60		SUV91_HUMAN (3602-3968): 3.98e-87: 294: 18.39