Interactor 1: M3K5 (O35099)
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
Gene: Map3k5

Interactor 2: ADA10 (O35598)
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene: Adam10

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 33601422
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0019901 - protein kinase binding
GO:0042803 - protein homodimerization activity
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1380
Mm

1 749
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024