HitPredict

Interactor 1: M3K5 (O35099)
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
Gene: Map3k5

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	28634551
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1380 Mm			1 817
+	Hs
		1071685 KS6A2_HUMAN (672-1337): 3.07e-122: 399: 13.92		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Hs
		1073494 KS6A1_HUMAN (636-1361): 4.53e-124: 404: 13.87		NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50
+	Hs
		647852 MARK3_HUMAN (638-1378): 6.03e-167: 519: 16.10		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		1183080 MARK2_HUMAN (637-1378): 2.5e-158: 498: 14.59		PAR3L_HUMAN (159-758): 1.59e-43: 172: 15.59
+	Hs
		876427 MARK2_HUMAN (637-1378): 2.5e-158: 498: 14.59		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		647882 MARK3_HUMAN (638-1378): 6.03e-167: 519: 16.10		PTN13_HUMAN (51-808): 7.26e-17: 88.2: 9.60
+	Hs
		647929 MARK3_HUMAN (638-1378): 6.03e-167: 519: 16.10		DLG5_HUMAN (424-594): 7.08e-09: 62: 18.75
+	Hs
		876374 ROCK1_HUMAN (668-1320): 1.1e-124: 422: 18.22		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		1073454 KS6A1_HUMAN (636-1361): 4.53e-124: 404: 13.87		PAR3L_HUMAN (159-758): 1.59e-43: 172: 15.59
+	Hs
		1183078 MARK2_HUMAN (637-1378): 2.5e-158: 498: 14.59		DLG5_HUMAN (424-594): 7.08e-09: 62: 18.75
+	Hs
		1073453 KS6A1_HUMAN (636-1361): 4.53e-124: 404: 13.87		LNX1_HUMAN (224-773): 4.36e-33: 138: 11.92
+	Hs
		1021498 KS6A2_HUMAN (672-1337): 3.07e-122: 399: 13.92		DLG1_HUMAN (80-763): 3.75e-33: 139: 11.22
+	Mm
		1143553 KS6A2_MOUSE (680-1337): 1.05e-122: 401: 14.08		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Hs
		942348 KS6A1_HUMAN (636-1361): 4.53e-124: 404: 13.87		DLG4_HUMAN (438-714): 1.14e-29: 127: 16.03
+	Hs
		1073434 KS6A1_HUMAN (636-1361): 4.53e-124: 404: 13.87		MAGI3_HUMAN (130-755): 5.88e-19: 94.7: 11.72
+	Hs
		1073470 KS6A1_HUMAN (636-1361): 4.53e-124: 404: 13.87		MAGI1_HUMAN (449-794): 5.95e-16: 84.7: 12.50
+	Hs
		883917 KS6A1_HUMAN (636-1361): 4.53e-124: 404: 13.87		SYJ2B_HUMAN (496-589): 9.67e-18: 82.7: 27.66
+	Hs
		1021556 M3K3_HUMAN (692-947): 2.28e-43: 170: 40.08		DLG1_HUMAN (80-763): 3.75e-33: 139: 11.22