HitPredict

Interactor 1: KDM6A (O15550)
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)
Gene: KDM6A

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1401 Hs			1 758
+	Hs
		161374 KDM6A_HUMAN (1-1401): 0: 1667: 100.00		KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76
+	Hs
		194588 KDM6A_HUMAN (1-1401): 0: 1667: 100.00		KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94
+	Hs
		158679 UTY_HUMAN (1-1393): 0: 1523: 83.49		KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76
+	Hs
		158698 UTY_HUMAN (1-1393): 0: 1523: 83.49		KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94
+	Hs
		185379 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		185700 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48
+	Hs
		1129777 CDC23_HUMAN (89-333): 4.95e-23: 107: 16.60		MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48
+	Hs
		185866 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94
+	Hs
		1401364 DNJC7_HUMAN (278-509): 2.61e-21: 101: 11.16		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46
+	Hs
		718565 CDC27_HUMAN (96-315): 1.8e-11: 71: 23.18		MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48