HitPredict

Interactor 1: A0A0A0MR80 (A0A0A0MR80)
E1A binding protein p400
Gene: EP400

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000812 - Swr1 complex GO:0035267 - NuA4 histone acetyltransferase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 985 Hs			1 1235
+	Hs
		1296839 EP400_HUMAN (1-983): 2.28e-118: 402: 99.70		BRD8_HUMAN (1-1235): 0: 594: 100.00
+	Hs
		1172547 E400N_HUMAN (28-505): 1.31e-45: 173: 83.05		BRD8_HUMAN (1-1235): 0: 594: 100.00
+	Mm
		101467 F8VPR5_MOUSE (229-791): 2.79e-38: 158: 16.31		KAT2B_MOUSE (1075-1209): 3.07e-37: 153: 22.96
+	Hs
		1270757 CBP_HUMAN (225-803): 8.79e-37: 153: 15.27		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		1342808 CHD7_HUMAN (170-970): 4.89e-41: 167: 12.86		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Mm
		101463 F8VPR5_MOUSE (229-791): 2.79e-38: 158: 16.31		TRI33_MOUSE (820-1232): 2.81e-31: 135: 11.78
+	Mm
		70879 F8VPR5_MOUSE (229-791): 2.79e-38: 158: 16.31		EP300_MOUSE (807-1211): 8.19e-30: 131: 15.12
+	Hs
		170437 CBP_HUMAN (225-803): 8.79e-37: 153: 15.27		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Mm
		292070 SMCA2_MOUSE (449-942): 1.25e-39: 162: 12.34		BRD7_MOUSE (1005-1212): 1.94e-28: 124: 15.49
+	Mm
		1150298 SMCA2_MOUSE (449-942): 1.25e-39: 162: 12.34		BAZ1B_MOUSE (555-840): 3.47e-27: 122: 15.73
+	Hs
		998940 CBP_HUMAN (225-803): 8.79e-37: 153: 15.27		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		1199209 CHD7_HUMAN (170-970): 4.89e-41: 167: 12.86		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Mm
		101535 SMCA2_MOUSE (449-942): 1.25e-39: 162: 12.34		F8VQD1_MOUSE (987-1226): 1.28e-22: 107: 15.45
+	Hs
		847103 CHD7_HUMAN (170-970): 4.89e-41: 167: 12.86		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		600103 SMCA2_HUMAN (449-942): 1.26e-36: 152: 11.62		TAF1_HUMAN (1002-1220): 5.29e-22: 105: 15.32
+	Dm
		631317 BRM_DROME (612-983): 1.78e-39: 161: 14.25		Q9VC36_DROME (504-1207): 1.3e-18: 94.3: 10.88
+	Hs
		847041 CBP_HUMAN (225-803): 8.79e-37: 153: 15.27		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Dm
		115984 BRM_DROME (612-983): 1.78e-39: 161: 14.25		M9PH39_DROME (622-802): 6.14e-14: 79.5: 23.28
+	Mm
		101468 F8VPR5_MOUSE (229-791): 2.79e-38: 158: 16.31		KAT2A_MOUSE (684-810): 1.09e-12: 74.9: 17.32
+	Hs
		1270755 CBP_HUMAN (225-803): 8.79e-37: 153: 15.27		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22