HitPredict

Interactor 1: NR1I3 (O35627)
Nuclear receptor subfamily 1 group I member 3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67)
Gene: NR1I3

Interactor 2: HS90B (P11499)
Heat shock protein HSP 90-beta (Heat shock 84 kDa) (HSP 84) (HSP84) (Tumor-specific transplantation 84 kDa antigen) (TSTA)
Gene: Hsp90ab1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12885400
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~Hormone_recep
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 358 Mm			1 724
+	Hs
		395346 ESR1_HUMAN (1-357): 8.3e-96: 298: 22.31		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		468379 NR1I3_HUMAN (12-358): 1.56e-98: 297: 73.22		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		343210 ERR2_HUMAN (17-357): 4.38e-96: 294: 25.66		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		468322 NR1H3_HUMAN (4-357): 6.56e-96: 294: 29.27		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		468077 NR4A1_HUMAN (2-357): 1.89e-92: 289: 25.14		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		395339 ESR1_HUMAN (1-357): 8.3e-96: 298: 22.31		HS90A_HUMAN (1-724): 0: 1066: 85.66
+	Hs
		461483 NR1I3_HUMAN (12-358): 1.56e-98: 297: 73.22		HS90A_HUMAN (1-724): 0: 1066: 85.66
+	Hs
		343207 ERR2_HUMAN (17-357): 4.38e-96: 294: 25.66		HS90A_HUMAN (1-724): 0: 1066: 85.66
+	Hs
		461425 NR1H3_HUMAN (4-357): 6.56e-96: 294: 29.27		HS90A_HUMAN (1-724): 0: 1066: 85.66
+	Hs
		282917 NR1I2_HUMAN (3-357): 6.81e-90: 278: 37.65		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		468006 VDR_HUMAN (1-357): 2.87e-90: 278: 33.89		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		282916 NR1I2_HUMAN (3-357): 6.81e-90: 278: 37.65		HS90A_HUMAN (1-724): 0: 1066: 85.66
+	Hs
		573342 RXRB_HUMAN (17-357): 3.12e-100: 308: 22.97		ENPL_HUMAN (3-696): 0: 912: 46.38
+	Hs
		395422 ESR1_HUMAN (1-357): 8.3e-96: 298: 22.31		ENPL_HUMAN (3-696): 0: 912: 46.38
+	Hs
		573329 NR4A1_HUMAN (2-357): 1.89e-92: 289: 25.14		ENPL_HUMAN (3-696): 0: 912: 46.38
+	Hs
		468139 PPARG_HUMAN (21-356): 3.73e-28: 116: 28.95		HS90B_HUMAN (1-724): 0: 1080: 99.59
+	Hs
		461226 PPARG_HUMAN (21-356): 3.73e-28: 116: 28.95		HS90A_HUMAN (1-724): 0: 1066: 85.66