HitPredict

Interactor 1: TGON2 (O43493)
Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)
Gene: TGOLN2

Interactor 2: AP1M1 (Q9BXS5)
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)
Gene: AP1M1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.731

Property	Details
Experiments	26186194, 28514442, 29568061, 15254094, 33961781, 10814565
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 423
+	Hs
		205817 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Hs
		206195 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		AP3M1_HUMAN (3-422): 5.32e-127: 375: 26.73
+	Rn
		587329 TGON3_RAT (97-436): 3.48e-34: 132: 40.00		AP2M1_RAT (3-421): 3.27e-155: 447: 38.85
+	Hs
		203244 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Rn
		587328 TGON3_RAT (97-436): 3.48e-34: 132: 40.00		AP3M1_RAT (3-422): 5.93e-127: 375: 26.73
+	Hs
		205756 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		STON2_HUMAN (125-422): 2.26e-71: 243: 21.85
+	Hs
		205162 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72