HitPredict

Interactor 1: A0A0B4J1S8 (A0A0B4J1S8)
Phosphatidylinositol 4-kinase beta (EC 2.7.1.67)
Gene: PI4KB

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	23572552
Identification Methods	gal4 vp16 complementation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~Ras, PI4KB-PIK1_PIK~Ras
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 828 Hs			1 218
+	Hs
		1155399 PI4KB_HUMAN (13-828): 0: 1163: 100.00		RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00
+	Mm
		857890 PI4KB_MOUSE (13-828): 0: 1161: 98.53		RB11B_MOUSE (1-218): 7.98e-94: 275: 99.08
+	Hs
		976631 PI4KB_HUMAN (13-828): 0: 1163: 100.00		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		958040 PI4KB_HUMAN (13-828): 0: 1163: 100.00		RAB14_HUMAN (1-214): 1.09e-83: 249: 44.65
+	Dm
		197392 Q9W0R8_DROME (133-828): 0: 778: 42.44		O18335_DROME (1-216): 1.86e-85: 253: 83.80
+	Hs
		976306 Q4LE69_HUMAN (505-827): 3.87e-111: 376: 34.65		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Sc
		649823 VPS34_YEAST (475-825): 1.63e-92: 312: 22.63		YPT31_YEAST (1-215): 1.5e-99: 289: 60.09
+	Hs
		839021 PK3CA_HUMAN (478-825): 2.52e-87: 301: 24.06		RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00
+	Sc
		649837 VPS34_YEAST (475-825): 1.63e-92: 312: 22.63		YPT32_YEAST (7-215): 9.36e-87: 257: 60.00
+	Hs
		956323 Q4LE69_HUMAN (505-827): 3.87e-111: 376: 34.65		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56
+	At
		1426578 P4KB1_ARATH (84-644): 4.24e-69: 250: 14.93		RAA4B_ARATH (9-215): 7.74e-82: 244: 58.45
+	Dm
		197325 Q7K3H0_DROME (566-816): 8.14e-22: 103: 28.85		O18335_DROME (1-216): 1.86e-85: 253: 83.80