Protein: HDGR2
Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2)

Gene: HDGR2, HDGFL2
Organism: Homo sapiens
Interactions: 170
UniProt ID: Q7Z4V5

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006281 - DNA repair
GO:0006310 - DNA recombination
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

934923

H31
Histone H3.1

3

20

High-throughput

0.827

High

260919

H2AY
Core histone macro-H2A.1

2

20

High-throughput

0.789

High

266032

PSIP1
PC4 and SFRS1-interacting protein

2

9

High-throughput

0.789

High

555526

H2AX
Histone H2AX

2

16

Small-scale

0.789

High

850940

HDGF
Hepatoma-derived growth factor

2

9

High-throughput

0.789

High

934278

CSK21
Casein kinase II subunit alpha

4

7

High-throughput

0.705

High

586830

CSK22
Casein kinase II subunit alpha'

4

8

High-throughput

0.699

High

1190732

H2AW
Core histone macro-H2A.2

1

20

High-throughput

0.691

High

1190745

HDGR3
Hepatoma-derived growth factor-related protein 3

1

9

High-throughput

0.691

High

827234

ARRB1
Beta-arrestin-1

3

1

High-throughput

0.671

High

1190744

KLH20
Kelch-like protein 20

3

1

High-throughput

0.667

High

1174587

H32
Histone H3.2

1

20

Small-scale

0.666

High

1190696

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.665

High

1189229

POGZ
Pogo transposable element with ZNF domain

3

9

Small-scale

0.656

High

244612

BRD4
Bromodomain-containing protein 4

3

20

High-throughput

0.640

High

685996

ARRB2
Beta-arrestin-2

2

1

High-throughput

0.628

High

1190703

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

2

4

High-throughput

0.628

High

828282

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

918474

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

952434

H33
Histone H3.3

1

20

High-throughput

0.618

High

331538

ACL6A
Actin-like protein 6A

2

5

High-throughput

0.611

High

447261

HXB5
Homeobox protein Hox-B5

2

7

High-throughput

0.611

High

738774

SPB5
Serpin B5

2

3

High-throughput

0.611

High

1190733

MBD5
Methyl-CpG-binding domain protein 5

2

0

High-throughput

0.585

High

1136669

H37
Histone H3-7

1

20

High-throughput

0.575

High

817696

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

2

High-throughput

0.574

High

1190735

DBF4A
Protein DBF4 homolog A

2

2

High-throughput

0.574

High

369905

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1130260

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

2

High-throughput

0.571

High

1074930

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.568

High

1190676

ZCHC7
Zinc finger CCHC domain-containing protein 7

2

5

High-throughput

0.558

High

783795

5HT2B
5-hydroxytryptamine receptor 2B

1

1

High-throughput

0.541

High

869677

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.541

High

117745

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.536

High

125899

CDC7
Cell division cycle 7-related protein kinase

1

4

High-throughput

0.536

High

207064

XRCC3
DNA repair protein XRCC3

1

2

High-throughput

0.536

High

846808

SMCA2
Probable global transcription activator SNF2L2

1

19

High-throughput

0.536

High

931705

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.536

High

942420

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

1

2

High-throughput

0.536

High

996736

SSRP1
FACT complex subunit SSRP1

1

16

High-throughput

0.536

High

1062558

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.536

High

1089480

TIGD6
Tigger transposable element-derived protein 6

1

2

High-throughput

0.536

High

1190684

ARI1B
AT-rich interactive domain-containing protein 1B

1

2

High-throughput

0.536

High

1190687

SMRC2
SWI/SNF complex subunit SMARCC2

1

8

High-throughput

0.536

High

1190691

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

2

High-throughput

0.536

High

1190693

DPF3
Zinc finger protein DPF3

1

20

High-throughput

0.536

High

1190694

SMRC1
SWI/SNF complex subunit SMARCC1

1

6

High-throughput

0.536

High

1190695

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

1

High-throughput

0.536

High

1190697

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

10

High-throughput

0.536

High

1190701

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

1

High-throughput

0.536

High

1190702

CDA7L
Cell division cycle-associated 7-like protein

1

1

High-throughput

0.536

High

1190706

SRPK1
SRSF protein kinase 1

1

4

High-throughput

0.536

High

1190707

IWS1
Protein IWS1 homolog

1

3

High-throughput

0.536

High

1190708

PARK7
Parkinson disease protein 7

1

1

High-throughput

0.536

High

1190711

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

2

High-throughput

0.536

High

1190737

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

1190739

PARP2
Poly [ADP-ribose] polymerase 2

1

12

High-throughput

0.536

High

1190700

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

9

High-throughput

0.515

High

51101

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

0

High-throughput

0.513

High

154504

MEIS2
Homeobox protein Meis2

1

0

High-throughput

0.513

High

824647

MAPK2
MAP kinase-activated protein kinase 2

1

0

High-throughput

0.513

High

957195

DAB2
Disabled homolog 2

1

0

High-throughput

0.513

High

970585

ID2
DNA-binding protein inhibitor ID-2

1

0

High-throughput

0.513

High

1113951

RABL6
Rab-like protein 6

1

0

High-throughput

0.513

High

1131587

ZMYM1
Zinc finger MYM-type protein 1

1

0

High-throughput

0.513

High

1158778

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.513

High

1190675

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

1190690

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

1190716

TOLIP
Toll-interacting protein

1

0

High-throughput

0.513

High

1190717

CARD9
Caspase recruitment domain-containing protein 9

1

0

High-throughput

0.513

High

1190723

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.513

High

1190724

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

1190734

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

1190740

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.513

High

839275

5HT6R
5-hydroxytryptamine receptor 6

1

1

High-throughput

0.494

High

361880

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

2

High-throughput

0.489

High

1070193

RASA2
Ras GTPase-activating protein 2

1

1

High-throughput

0.489

High

1102130

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

2

High-throughput

0.489

High

1129388

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

1

10

High-throughput

0.489

High

1132876

MPP7
MAGUK p55 subfamily member 7

1

1

High-throughput

0.489

High

1134915

SYT6
Synaptotagmin-6

1

1

High-throughput

0.489

High

1190680

SYT2
Synaptotagmin-2

1

1

High-throughput

0.489

High

1190686

VANG1
Vang-like protein 1

1

1

High-throughput

0.489

High

1190688

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

2

High-throughput

0.489

High

1190699

NSUN4
5-methylcytosine rRNA methyltransferase NSUN4

1

2

High-throughput

0.489

High

1190710

SEM3C
Semaphorin-3C

1

5

High-throughput

0.489

High

1190714

RFIP5
Rab11 family-interacting protein 5

1

2

High-throughput

0.489

High

1190730

FKB11
Peptidyl-prolyl cis-trans isomerase FKBP11

1

1

High-throughput

0.489

High

1190741

VANG2
Vang-like protein 2

1

1

High-throughput

0.489

High

1190746

WIF1
Wnt inhibitory factor 1

1

1

High-throughput

0.489

High

227905

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

258086

DNJB6
DnaJ homolog subfamily B member 6

1

2

High-throughput

0.479

High

278833

DNJC8
DnaJ homolog subfamily C member 8

1

3

High-throughput

0.479

High

282283

CDKL5
Cyclin-dependent kinase-like 5

1

3

High-throughput

0.479

High

295812

ST17B
Serine/threonine-protein kinase 17B

1

5

High-throughput

0.479

High

317468

YETS4
YEATS domain-containing protein 4

1

2

High-throughput

0.479

High

360092

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

11

High-throughput

0.479

High

379552

MYCN
N-myc proto-oncogene protein

1

10

High-throughput

0.479

High

455598

PARP1
Poly [ADP-ribose] polymerase 1

1

20

High-throughput

0.479

High

523845

XRCC6
X-ray repair cross-complementing protein 6

1

7

High-throughput

0.479

High

533226

PLSL
Plastin-2

1

3

High-throughput

0.479

High

569842

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.479

High

582363

NUCL
Nucleolin

1

5

High-throughput

0.479

High

609932

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

3

High-throughput

0.479

High

631483

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

642422

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.479

High

652899

APEX1
DNA repair nuclease/redox regulator APEX1

1

7

High-throughput

0.479

High

720801

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

841252

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

870841

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.479

High

903336

WDR5
WD repeat-containing protein 5

1

9

High-throughput

0.479

High

908750

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

917505

H4
Histone H4

1

8

High-throughput

0.479

High

932229

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.479

High

949500

RL24
Large ribosomal subunit protein eL24

1

1

High-throughput

0.479

High

949825

CBX1
Chromobox protein homolog 1

1

18

Small-scale

0.479

High

967248

EWS
RNA-binding protein EWS

1

3

High-throughput

0.479

High

1027088

CBX3
Chromobox protein homolog 3

1

18

High-throughput

0.479

High

1059699

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

15

High-throughput

0.479

High

1064443

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1080075

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.479

High

1170594

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1190672

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1190674

SMC5
Structural maintenance of chromosomes protein 5

1

12

High-throughput

0.479

High

1190682

CSK23
Casein kinase II subunit alpha 3

1

7

High-throughput

0.479

High

1190683

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1190689

DUS19
Dual specificity protein phosphatase 19

1

1

High-throughput

0.479

High

1190692

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1190698

FBXW7
F-box/WD repeat-containing protein 7

1

7

High-throughput

0.479

High

1190709

CTIP
DNA endonuclease RBBP8

1

1

Small-scale

0.479

High

1190713

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1190718

ADNP
Activity-dependent neuroprotector homeobox protein

1

2

High-throughput

0.479

High

1190719

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1190727

DJC17
DnaJ homolog subfamily C member 17

1

2

High-throughput

0.479

High

1190736

ST17A
Serine/threonine-protein kinase 17A

1

5

High-throughput

0.479

High

1190738

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1190742

FBW1A
F-box/WD repeat-containing protein 1A

1

7

High-throughput

0.479

High

233524

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

1190673

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1190681

CC020
Uncharacterized protein C3orf20

1

0

High-throughput

0.458

High

1190712

IER2
Immediate early response gene 2 protein

1

0

High-throughput

0.458

High

1190722

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.458

High

1190725

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1190728

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1190731

DJC27
DnaJ homolog subfamily C member 27

1

0

High-throughput

0.458

High

1190677

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

1190685

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

1

High-throughput

0.445

High

148995

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.437

High

385084

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

887194

DJB13
DnaJ homolog subfamily B member 13

1

1

High-throughput

0.437

High

1153857

IFIX
Pyrin and HIN domain-containing protein 1

1

7

High-throughput

0.437

High

1190704

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

2

High-throughput

0.437

High

1190720

DJC18
DnaJ homolog subfamily C member 18

1

3

High-throughput

0.437

High

1190726

DJC11
DnaJ homolog subfamily C member 11

1

3

High-throughput

0.437

High

1190743

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.437

High

664100

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.328

High

674861

AGTR1
Type-1 angiotensin II receptor

1

0

High-throughput

0.282

High

270201

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.279

Low

964791

AMPD2
AMP deaminase 2

1

0

High-throughput

0.279

Low

1190671

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

1190678

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

1190679

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

1190705

F218A
Protein FAM218A

1

0

High-throughput

0.279

Low

1190715

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.279

Low

531885

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.269

Low

168268

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.249

Low

643887

SYVC
Valine--tRNA ligase

1

0

High-throughput

0.249

Low

1153658

PTCRA
Pre T-cell antigen receptor alpha

1

0

High-throughput

0.249

Low

1190721

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

1190729

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024