HitPredict

Interactor 1: TNF14 (O43557)
Tumor necrosis factor ligand superfamily member 14 (Herpes virus entry mediator ligand) (HVEM-L) (Herpesvirus entry mediator ligand) (CD antigen CD258) [Cleaved into: Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form]
Gene: TNFSF14

Interactor 2: TNR3 (P36941)
Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III)
Gene: LTBR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 12571250, 10799510, 26977880
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, enzyme linked immunosorbent assay, yeast display
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~TNFR_c6
Common GO terms GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0006955 - immune response
GO:0007165 - signal transduction
GO:0071260 - cellular response to mechanical stimulus
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 240
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024