HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~SH3_1, SH3_1~SH3_1, SH3_9~SH3_9
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001771 - immunological synapse formation
GO:0001784 - phosphotyrosine residue binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
and 27 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 380
Hs

1 380
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Last updated: 15 Jul 2024