HitPredict

Interactor 1: SIGL6 (O43699)
Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327)
Gene: SIGLEC6

Interactor 2: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19150402
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007267 - cell-cell signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 453 Hs			1 128
+	Hs
		243162 SIGL7_HUMAN (23-453): 3.93e-74: 241: 50.11		SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00
+	Hs
		434111 ROBO1_HUMAN (29-445): 6.46e-59: 211: 14.52		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Hs
		434019 ROBO2_HUMAN (29-436): 1.08e-57: 207: 14.89		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Hs
		155860 ROBO1_HUMAN (29-445): 6.46e-59: 211: 14.52		SH21B_HUMAN (5-119): 1.69e-34: 117: 42.61
+	Hs
		433569 CD22_HUMAN (30-452): 2.52e-44: 167: 17.95		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Hs
		590610 CD22_HUMAN (30-452): 2.52e-44: 167: 17.95		SHIP1_HUMAN (4-103): 1.66e-37: 136: 43.00
+	Hs
		243129 CD22_HUMAN (30-452): 2.52e-44: 167: 17.95		SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00
+	Hs
		590607 CD22_HUMAN (30-452): 2.52e-44: 167: 17.95		GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69
+	Hs
		522764 CD33_HUMAN (143-452): 2.68e-39: 146: 20.23		SRC_HUMAN (1-127): 8.71e-39: 138: 20.90
+	Hs
		433742 PTK7_HUMAN (27-374): 4.31e-30: 125: 12.60		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Dm
		219802 O44924_DROME (2-253): 8.99e-26: 112: 14.01		ABL_DROME (1-127): 2.37e-39: 141: 27.82
+	Hs
		177593 SIGL5_HUMAN (44-453): 2.75e-27: 116: 17.12		SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00
+	Hs
		590606 CD22_HUMAN (30-452): 2.52e-44: 167: 17.95		KSYK_HUMAN (6-120): 2.74e-15: 72.8: 25.86
+	Hs
		433249 VCAM1_HUMAN (105-365): 6.87e-20: 94.4: 19.42		YES_HUMAN (1-127): 2.68e-40: 142: 19.40
+	Hs
		412004 MAG_HUMAN (29-451): 2.54e-20: 95.7: 12.92		FYN_HUMAN (1-125): 4.91e-37: 133: 18.52
+	Hs
		176379 VCAM1_HUMAN (105-365): 6.87e-20: 94.4: 19.42		SHIP2_HUMAN (3-122): 1.12e-34: 128: 37.50
+	Hs
		523003 MYLK_HUMAN (246-337): 2.58e-16: 83.9: 20.20		SRC_HUMAN (1-127): 8.71e-39: 138: 20.90
+	Hs
		589563 CD33_HUMAN (143-452): 2.68e-39: 146: 20.23		KSYK_HUMAN (6-120): 2.74e-15: 72.8: 25.86
+	Hs
		581649 VCAM1_HUMAN (105-365): 6.87e-20: 94.4: 19.42		GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69
+	Hs
		581520 VCAM1_HUMAN (105-365): 6.87e-20: 94.4: 19.42		KSYK_HUMAN (6-120): 2.74e-15: 72.8: 25.86