HitPredict

Interactor 1: TSN6 (O43657)
Tetraspanin-6 (Tspan-6) (A15 homolog) (Putative NF-kappa-B-activating protein 321) (T245 protein) (Tetraspanin TM4-D) (Transmembrane 4 superfamily member 6)
Gene: TSPAN6

Interactor 2: TSN15 (O95858)
Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)
Gene: TSPAN15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 294
+	Hs
		349402 TSN5_HUMAN (6-238): 2.44e-63: 200: 24.23		TSN15_HUMAN (1-294): 2.67e-95: 284: 100.00
+	Hs
		349362 CD63_HUMAN (8-239): 9.66e-63: 197: 28.21		TSN15_HUMAN (1-294): 2.67e-95: 284: 100.00
+	Hs
		349393 CD151_HUMAN (3-242): 7.15e-62: 196: 27.78		TSN15_HUMAN (1-294): 2.67e-95: 284: 100.00
+	Hs
		349494 TSN14_HUMAN (7-238): 1.32e-60: 193: 23.17		TSN15_HUMAN (1-294): 2.67e-95: 284: 100.00
+	Hs
		967327 TSN5_HUMAN (6-238): 2.44e-63: 200: 24.23		TSN14_HUMAN (9-268): 1.08e-76: 236: 31.46
+	Hs
		873784 CD151_HUMAN (3-242): 7.15e-62: 196: 27.78		TSN14_HUMAN (9-268): 1.08e-76: 236: 31.46
+	Hs
		873767 TSN5_HUMAN (6-238): 2.44e-63: 200: 24.23		CD151_HUMAN (13-264): 1.97e-58: 189: 22.96
+	Hs
		298987 TSN5_HUMAN (6-238): 2.44e-63: 200: 24.23		TSN9_HUMAN (13-266): 8.75e-58: 187: 23.64
+	Hs
		477405 CD63_HUMAN (8-239): 9.66e-63: 197: 28.21		CD82_HUMAN (13-264): 1.6e-56: 184: 17.80
+	Hs
		697351 CD151_HUMAN (3-242): 7.15e-62: 196: 27.78		CD82_HUMAN (13-264): 1.6e-56: 184: 17.80
+	Hs
		641933 TSN5_HUMAN (6-238): 2.44e-63: 200: 24.23		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		948746 TSN5_HUMAN (6-238): 2.44e-63: 200: 24.23		CD81_HUMAN (11-262): 3.86e-52: 172: 15.53
+	Hs
		477403 CD63_HUMAN (8-239): 9.66e-63: 197: 28.21		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		641923 CD151_HUMAN (3-242): 7.15e-62: 196: 27.78		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		873766 CD151_HUMAN (3-242): 7.15e-62: 196: 27.78		CD81_HUMAN (11-262): 3.86e-52: 172: 15.53
+	Hs
		641966 TSN14_HUMAN (7-238): 1.32e-60: 193: 23.17		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		252650 CD63_HUMAN (8-239): 9.66e-63: 197: 28.21		TSN3_HUMAN (13-274): 5.16e-50: 167: 20.23
+	Hs
		873787 CD151_HUMAN (3-242): 7.15e-62: 196: 27.78		TSN18_HUMAN (16-260): 1.18e-47: 161: 18.47