HitPredict

Interactor 1: TSN3 (O60637)
Tetraspanin-3 (Tspan-3) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8)
Gene: TSPAN3

Interactor 2: CD63 (P08962)
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)
Gene: CD63

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 238
+	Hs
		477405 CD82_HUMAN (1-243): 1.28e-58: 188: 26.72		CD63_HUMAN (1-238): 7.31e-68: 210: 100.00
+	Hs
		873767 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		CD151_HUMAN (3-232): 1.16e-59: 190: 28.22
+	Hs
		873784 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		TSN14_HUMAN (11-235): 5.9e-58: 186: 27.20
+	Hs
		967327 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		TSN14_HUMAN (11-235): 5.9e-58: 186: 27.20
+	Hs
		298987 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		TSN9_HUMAN (4-233): 5.53e-57: 182: 30.04
+	Hs
		641923 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		CD9_HUMAN (1-238): 5.75e-54: 174: 24.49
+	Hs
		641933 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		CD9_HUMAN (1-238): 5.75e-54: 174: 24.49
+	Hs
		298986 TSN9_HUMAN (1-240): 1.47e-61: 195: 24.58		CD9_HUMAN (1-238): 5.75e-54: 174: 24.49
+	Hs
		873766 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		CD81_HUMAN (1-234): 4.36e-53: 172: 22.04
+	Hs
		948746 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		CD81_HUMAN (1-234): 4.36e-53: 172: 22.04
+	Hs
		252648 TSN3_HUMAN (1-253): 1.8e-66: 208: 100.00		TSN15_HUMAN (10-232): 5.78e-47: 158: 23.97
+	Hs
		697351 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		CD82_HUMAN (4-234): 8.23e-52: 170: 24.13
+	Hs
		641915 CD82_HUMAN (1-243): 1.28e-58: 188: 26.72		CD9_HUMAN (1-238): 5.75e-54: 174: 24.49
+	Hs
		349393 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		TSN15_HUMAN (10-232): 5.78e-47: 158: 23.97
+	Hs
		349402 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		TSN15_HUMAN (10-232): 5.78e-47: 158: 23.97
+	Hs
		298985 TSN9_HUMAN (1-240): 1.47e-61: 195: 24.58		TSN15_HUMAN (10-232): 5.78e-47: 158: 23.97
+	Hs
		622031 CD82_HUMAN (1-243): 1.28e-58: 188: 26.72		CD53_HUMAN (1-238): 1.7e-50: 165: 26.47