HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: PININ (Q9H307)
Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)
Gene: PNN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26641092, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 717
+	Hs
		1020329 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		1054583 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		1329867 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		1031460 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00