HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: FLNB (Q80X90)
Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin)
Gene: FLNB

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	30333137
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filamin~Integrin_b_cyt
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 787 Mm			1 2602
+	Hs
		261179 ITB3_HUMAN (1-787): 0: 763: 90.61		FLNB_HUMAN (1-2602): 0: 2446: 95.85
+	Hs
		261181 ITB1_HUMAN (10-786): 0: 728: 43.52		FLNB_HUMAN (1-2602): 0: 2446: 95.85
+	Hs
		261196 ITB6_HUMAN (30-785): 0: 692: 49.87		FLNB_HUMAN (1-2602): 0: 2446: 95.85
+	Mm
		222557 ITB3_MOUSE (1-787): 0: 793: 100.00		FLNA_MOUSE (1-2602): 0: 2286: 68.64
+	Hs
		396566 ITB3_HUMAN (1-787): 0: 763: 90.61		FLNA_HUMAN (1-2602): 0: 2272: 68.98
+	Mm
		447108 ITB1_MOUSE (10-786): 0: 733: 43.27		FLNA_MOUSE (1-2602): 0: 2286: 68.64
+	Hs
		403783 ITB1_HUMAN (10-786): 0: 728: 43.52		FLNA_HUMAN (1-2602): 0: 2272: 68.98
+	Hs
		577567 ITB6_HUMAN (30-785): 0: 692: 49.87		FLNA_HUMAN (1-2602): 0: 2272: 68.98
+	Mm
		222569 ITB3_MOUSE (1-787): 0: 793: 100.00		FLNC_MOUSE (7-2602): 0: 1228: 35.09
+	Mm
		222535 ITB3_MOUSE (1-787): 0: 793: 100.00		SPTB2_MOUSE (6-370): 7.45e-104: 376: 27.85
+	Mm
		447075 ITB1_MOUSE (10-786): 0: 733: 43.27		ACTN4_MOUSE (12-241): 1.67e-104: 361: 35.90
+	Gg
		396530 ITB1_CHICK (8-786): 0: 729: 43.23		ACTN1_CHICK (5-355): 8.19e-100: 346: 26.72
+	Hs
		403752 ITB1_HUMAN (10-786): 0: 728: 43.52		ACTN1_HUMAN (5-241): 4.76e-95: 332: 36.10
+	Rn
		88558 ITB1_RAT (10-786): 0: 726: 43.09		D3ZCV0_RAT (5-241): 4.04e-95: 332: 36.52
+	Hs
		362672 ITB3_HUMAN (1-787): 0: 763: 90.61		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Hs
		362680 ITB1_HUMAN (10-786): 0: 728: 43.52		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Hs
		362793 ITB5_HUMAN (4-787): 0: 710: 53.63		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Hs
		362796 ITB6_HUMAN (30-785): 0: 692: 49.87		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Hs
		362834 ITB7_HUMAN (31-785): 0: 637: 38.82		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Hs
		574558 ITB5_HUMAN (4-787): 0: 710: 53.63		TITIN_HUMAN (372-1206): 4.15e-09: 64.8: 9.61