HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Hs			1 95
+	Hs
		965372 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		LSM4_HUMAN (1-87): 3.26e-32: 110: 32.58
+	Hs
		964811 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		SMD1_HUMAN (1-95): 6.69e-29: 101: 28.42
+	Hs
		964813 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		SMD3_HUMAN (2-88): 6.47e-24: 89.6: 20.69
+	Hs
		964810 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		RUXF_HUMAN (3-71): 2.46e-23: 86.9: 31.43
+	Hs
		222550 PLRG1_HUMAN (2-333): 4.67e-85: 267: 26.05		LSM2_HUMAN (1-95): 4.23e-38: 124: 100.00
+	Hs
		222463 PLRG1_HUMAN (2-333): 4.67e-85: 267: 26.05		RUXF_HUMAN (3-71): 2.46e-23: 86.9: 31.43
+	Hs
		974830 WDR83_HUMAN (25-333): 4.3e-84: 258: 31.83		SMD3_HUMAN (2-88): 6.47e-24: 89.6: 20.69
+	Hs
		974030 WDR83_HUMAN (25-333): 4.3e-84: 258: 31.83		RUXF_HUMAN (3-71): 2.46e-23: 86.9: 31.43
+	Dm
		232187 Q9VPL0_DROME (79-333): 1.15e-67: 217: 24.53		SMD3_DROME (2-74): 2.75e-23: 88.4: 23.29
+	Hs
		1180267 SMU1_HUMAN (30-331): 7.69e-39: 145: 28.71		LSM4_HUMAN (1-87): 3.26e-32: 110: 32.58
+	Hs
		973935 SMU1_HUMAN (30-331): 7.69e-39: 145: 28.71		RUXF_HUMAN (3-71): 2.46e-23: 86.9: 31.43
+	Hs
		209358 PRP4_HUMAN (212-333): 3.64e-24: 104: 25.98		LSM2_HUMAN (1-95): 4.23e-38: 124: 100.00
+	Hs
		974440 FBXW7_HUMAN (198-333): 3.33e-28: 117: 30.15		SMD1_HUMAN (1-95): 6.69e-29: 101: 28.42
+	Hs
		209361 PRP4_HUMAN (212-333): 3.64e-24: 104: 25.98		LSM4_HUMAN (1-87): 3.26e-32: 110: 32.58
+	Hs
		974805 FBXW7_HUMAN (198-333): 3.33e-28: 117: 30.15		SMD3_HUMAN (2-88): 6.47e-24: 89.6: 20.69
+	Hs
		209239 PRP4_HUMAN (212-333): 3.64e-24: 104: 25.98		SMD3_HUMAN (2-88): 6.47e-24: 89.6: 20.69
+	Hs
		209234 PRP4_HUMAN (212-333): 3.64e-24: 104: 25.98		RUXF_HUMAN (3-71): 2.46e-23: 86.9: 31.43
+	Hs
		974444 SNR40_HUMAN (248-333): 4.75e-13: 70.8: 25.29		SMD1_HUMAN (1-95): 6.69e-29: 101: 28.42
+	Hs
		974811 SNR40_HUMAN (248-333): 4.75e-13: 70.8: 25.29		SMD3_HUMAN (2-88): 6.47e-24: 89.6: 20.69
+	Hs
		974009 SNR40_HUMAN (248-333): 4.75e-13: 70.8: 25.29		RUXF_HUMAN (3-71): 2.46e-23: 86.9: 31.43