HitPredict

Interactor 1: MDM35 (O60200)
Mitochondrial distribution and morphology protein 35
Gene: MDM35

Interactor 2: UPS3 (Q04006)
Protein UPS3, mitochondrial (Genetic interactor of prohibitins protein 2) (Unprocessed MGM1 protein 3)
Gene: UPS3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.802

Property	Details
Experiments	32051233, 20622808
Identification Methods	cross-linking study, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PRELI~UPF0203
Common GO terms	GO:0005739 - mitochondrion GO:0005758 - mitochondrial intermembrane space GO:0007005 - mitochondrion organization GO:0015914 - phospholipid transport GO:1990050 - phosphatidic acid transfer activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 86 Sc			1 179
+	Sc
		224235 MDM35_YEAST (1-86): 7.02e-43: 135: 100.00		UPS2_YEAST (1-175): 1.21e-74: 225: 56.57
+	Sc
		224238 MDM35_YEAST (1-86): 7.02e-43: 135: 100.00		UPS1_YEAST (3-172): 7.81e-55: 172: 23.53
+	Hs
		212031 TRIA1_HUMAN (8-62): 4.12e-24: 88.2: 43.64		PLD3B_HUMAN (1-171): 4.64e-67: 204: 31.40
+	Hs
		212022 TRIA1_HUMAN (8-62): 4.12e-24: 88.2: 43.64		PLD3A_HUMAN (1-167): 1.78e-63: 194: 29.17
+	Hs
		212030 TRIA1_HUMAN (8-62): 4.12e-24: 88.2: 43.64		PRLD1_HUMAN (1-171): 8.03e-58: 182: 28.90