Interactor 1: KPRB (O60256)
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41)
Gene: PRPSAP2

Interactor 2: KPRB (O60256)
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41)
Gene: PRPSAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyl_synth~Pribosyl_synth, Pribosyl_synth~Pribosyltran_N, Pribosyltran_N~Pribosyltran_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0002189 - ribose phosphate diphosphokinase complex
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0004857 - enzyme inhibitor activity
GO:0005524 - ATP binding
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 369
Hs

1 369
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024