HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: GHC1 (Q9H936)
Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22)
Gene: SLC25A22

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	32929329, 35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 323
+	Hs
		226378 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT1_HUMAN (97-322): 2.72e-38: 139: 19.48
+	Hs
		226250 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		226942 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Hs
		229010 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65
+	Hs
		226076 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		S2512_HUMAN (2-106): 1.04e-20: 94.6: 25.47
+	Hs
		227780 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SCMC1_HUMAN (215-313): 2.81e-17: 84.2: 17.17
+	Hs
		227774 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SCMC2_HUMAN (225-312): 1.47e-15: 78.8: 22.73
+	Hs
		226379 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT3_HUMAN (224-322): 3.75e-13: 70.7: 25.49
+	Hs
		858319 HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Hs
		1317097 HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65
+	Hs
		476538 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65