HitPredict

Interactor 1: LZTS3 (O60299)
Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1)
Gene: LZTS3

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 673 Hs			1 474
+	Hs
		1081135 LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		1081061 MTUS2_HUMAN (68-613): 1.72e-22: 105: 12.02		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		944678 MAP1A_HUMAN (71-671): 1.23e-26: 118: 12.38		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		1078835 MTUS2_HUMAN (68-613): 1.72e-22: 105: 12.02		ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38
+	Hs
		1201957 MRCKB_HUMAN (437-672): 3.14e-14: 78.8: 12.19		TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46
+	Hs
		149043 ANR35_HUMAN (71-671): 5.62e-28: 122: 15.05		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78
+	Hs
		61738 EP15R_HUMAN (503-671): 2.63e-13: 75.3: 10.47		A6H8W8_HUMAN (55-316): 4.69e-24: 108: 19.93
+	Hs
		944680 MAP1A_HUMAN (71-671): 1.23e-26: 118: 12.38		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Hs
		1078923 EP15R_HUMAN (503-671): 2.63e-13: 75.3: 10.47		ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38
+	Hs
		148554 SMCA4_HUMAN (52-566): 7.09e-26: 116: 13.95		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78
+	Hs
		724989 LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Rn
		222476 MRCKA_RAT (76-592): 3.25e-13: 75.3: 11.22		MRCKB_RAT (23-351): 1.72e-21: 100: 15.25
+	Hs
		1137917 MRCKA_HUMAN (76-566): 3.99e-13: 75.3: 9.53		MRCKB_HUMAN (23-351): 2.44e-20: 96.6: 14.57
+	Hs
		1268083 LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		724687 MYH10_HUMAN (189-642): 3.07e-14: 78.8: 8.70		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		1268126 MRCKB_HUMAN (437-672): 3.14e-14: 78.8: 12.19		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		528432 MYH13_HUMAN (324-645): 4.13e-15: 81.5: 21.41		MYH8_HUMAN (28-321): 5.06e-09: 61.1: 10.54
+	Hs
		725097 MYH10_HUMAN (189-642): 3.07e-14: 78.8: 8.70		MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07
+	Hs
		148461 MYH10_HUMAN (189-642): 3.07e-14: 78.8: 8.70		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78
+	Hs
		725095 MYH10_HUMAN (189-642): 3.07e-14: 78.8: 8.70		MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39