HitPredict

Interactor 1: AQR (O60306)
RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160)
Gene: AQR

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	22365833, 26186194, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1485 Hs			1 315
+	Hs
		209359 AQR_HUMAN (1-1485): 0: 1837: 100.00		PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15
+	Hs
		230786 AQR_HUMAN (1-1485): 0: 1837: 100.00		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Sp
		293526 CWF11_SCHPO (19-1376): 0: 1071: 22.84		YN55_SCHPO (28-288): 7.99e-72: 225: 41.60
+	Sp
		195161 CWF11_SCHPO (19-1376): 0: 1071: 22.84		PRP17_SCHPO (224-306): 1.02e-11: 67.5: 16.47
+	Hs
		1188042 SETX_HUMAN (563-1469): 1.88e-133: 460: 13.54		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		903572 ZNFX1_HUMAN (1002-1326): 3.04e-82: 301: 29.70		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		1272286 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		903413 RENT1_HUMAN (551-940): 2.94e-69: 257: 16.31		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		758134 SMBP2_HUMAN (747-975): 1.78e-29: 129: 18.46		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54