Protein: EXTL2
Exostosin-like 2 (EC 2.4.1.223) (Alpha-1,4-N-acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) [Cleaved into: Processed exostosin-like 2]

Gene: EXTL2
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q9UBQ6

Gene Ontology (top 5):
GO:0001888 - glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
GO:0005539 - glycosaminoglycan binding
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1329325

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

3

0

High-throughput

0.634

High

1452319

SCN3B
Sodium channel regulatory subunit beta-3

3

0

High-throughput

0.634

High

1350097

SPP2B
Signal peptide peptidase-like 2B

2

1

High-throughput

0.628

High

533790

CLUS
Clusterin

2

0

High-throughput

0.602

High

1164225

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.602

High

1389613

SAAL1
Protein SAAL1

2

1

High-throughput

0.601

High

783058

CXG1
Gap junction gamma-1 protein

2

0

High-throughput

0.576

High

1157142

KCA10
Potassium voltage-gated channel subfamily A member 10

2

1

High-throughput

0.574

High

1251817

S39A5
Zinc transporter ZIP5

2

12

High-throughput

0.574

High

1366289

LPAR1
Lysophosphatidic acid receptor 1

2

2

High-throughput

0.558

High

252567

TSN1
Tetraspanin-1

1

2

High-throughput

0.536

High

349600

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

518923

CCL3
C-C motif chemokine 3

1

2

High-throughput

0.536

High

593519

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.536

High

733723

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

5

High-throughput

0.536

High

1359265

CA054
Uncharacterized protein C1orf54

1

3

High-throughput

0.536

High

1372413

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.536

High

1436650

IPPK
Inositol-pentakisphosphate 2-kinase

1

1

High-throughput

0.536

High

302090

SEGN
Secretagogin

1

0

High-throughput

0.513

High

1203821

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1404260

SEC62
Translocation protein SEC62

1

0

High-throughput

0.513

High

1411652

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.513

High

1458632

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

1419248

TRI54
Tripartite motif-containing protein 54

1

1

High-throughput

0.494

High

570623

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.493

High

1279782

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1360769

JPH3
Junctophilin-3

1

0

High-throughput

0.493

High

168463

NCTR3
Natural cytotoxicity triggering receptor 3

1

1

High-throughput

0.489

High

380371

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

7

High-throughput

0.489

High

663507

PRPH2
Peripherin-2

1

2

High-throughput

0.489

High

1101434

SG2A2
Mammaglobin-A

1

4

High-throughput

0.489

High

1242967

S39A4
Zinc transporter ZIP4

1

12

High-throughput

0.489

High

1309003

S22A9
Organic anion transporter 7

1

3

High-throughput

0.489

High

1316004

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

1340719

CC4L
C-C motif chemokine 4-like

1

2

High-throughput

0.489

High

1363155

CLC2B
C-type lectin domain family 2 member B

1

5

High-throughput

0.489

High

1418357

TMPSD
Transmembrane protease serine 13

1

4

High-throughput

0.489

High

1421369

S39A8
Metal cation symporter ZIP8

1

12

High-throughput

0.489

High

218907

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

1272891

RFIP2
Rab11 family-interacting protein 2

1

1

High-throughput

0.479

High

1458631

GOT1B
Vesicle transport protein GOT1B

1

1

High-throughput

0.479

High

1136403

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.458

High

1326939

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

1330427

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1346818

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

9

High-throughput

0.445

High

1348082

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.445

High

1093598

TRDN
Triadin

1

0

High-throughput

0.426

High

1407824

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.426

High

380596

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

6

High-throughput

0.407

High

851233

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

5

High-throughput

0.407

High

1236365

MFSD5
Molybdate-anion transporter

1

3

High-throughput

0.407

High

1242262

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.407

High

1337994

ZNT7
Zinc transporter 7

1

9

High-throughput

0.407

High

125060

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.279

Low

231023

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.279

Low

260980

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

1407120

MDFI
MyoD family inhibitor

1

0

High-throughput

0.279

Low

1458504

MGT4C
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

1

0

High-throughput

0.279

Low

1208676

NTCP5
Sodium/bile acid cotransporter 5

1

0

High-throughput

0.232

Low

1235749

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

0

High-throughput

0.232

Low

1331870

SYT2
Synaptotagmin-2

1

0

High-throughput

0.232

Low

1355940

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.232

Low

1458630

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025