Interactor 1: OPA1 (O60313)
Dynamin-like GTPase OPA1, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1) [Cleaved into: Dynamin-like GTPase OPA1, long form (L-OPA1); Dynamin-like GTPase OPA1, short form (S-OPA1)]
Gene: OPA1

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.588

The method score is based on:

Property Details
Experiments 24282027, unassigned1853
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000287 - magnesium ion binding
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 9 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 960
Hs

1 2527
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ At
+ Hs
+ Ce

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Last updated: 15 Jul 2024