Interactor 1: SPY (O44783)
Protein sprouty (Spry)
Gene: sty
Interactor 2: O46034 (O46034)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: Cbl
Species: Drosophila melanogaster
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.24 | 0.60 | 0.381 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned4 |
| Identification Methods | experimental interaction detection |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0042059 - negative regulation of epidermal growth factor receptor signaling pathway |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
