HitPredict

Interactor 1: MPZL2 (O60487)
Myelin protein zero-like protein 2 (Epithelial V-like antigen 1)
Gene: MPZL2

Interactor 2: DRB1 (P01911)
HLA class II histocompatibility antigen, DRB1 beta chain (Human leukocyte antigen DRB1) (HLA-DRB1)
Gene: HLA-DRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~V-set, MHC_II_beta~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 266
+	Hs
		234741 MPZL2_HUMAN (1-215): 2.29e-59: 187: 100.00		DRB3_HUMAN (1-266): 1.45e-103: 303: 89.10
+	Hs
		354971 BT2A2_HUMAN (24-214): 1.8e-32: 124: 15.20		DRB1_HUMAN (1-266): 2.01e-107: 313: 100.00
+	Hs
		355002 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		DRB1_HUMAN (1-266): 2.01e-107: 313: 100.00
+	Hs
		382384 CXAR_HUMAN (8-213): 1.22e-34: 127: 20.00		HLAA_HUMAN (34-256): 9.63e-95: 284: 22.12
+	Hs
		945222 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		DRB3_HUMAN (1-266): 1.45e-103: 303: 89.10
+	Hs
		355067 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		DQB1_HUMAN (3-255): 2.06e-96: 285: 62.85
+	Hs
		382554 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		HLAA_HUMAN (34-256): 9.63e-95: 284: 22.12
+	Hs
		1278670 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		HMR1_HUMAN (38-258): 1.25e-73: 229: 25.45
+	Hs
		588783 BT2A1_HUMAN (19-214): 2.77e-34: 129: 14.42		DPA1_HUMAN (126-256): 3.03e-13: 69.7: 28.89
+	Hs
		1103649 BT2A2_HUMAN (24-214): 1.8e-32: 124: 15.20		HFE_HUMAN (58-237): 1.01e-11: 65.9: 27.03
+	Hs
		1103672 NECT3_HUMAN (18-205): 1.86e-29: 116: 17.62		HFE_HUMAN (58-237): 1.01e-11: 65.9: 27.03
+	Hs
		354786 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		DRA_HUMAN (117-217): 2.61e-10: 61.2: 30.69