HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: CSK (P41241)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK)
Gene: CSK

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24558484
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005911 - cell-cell junction GO:0010989 - negative regulation of low-density lipoprotein particle clearance GO:0046872 - metal ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 787 Mm			1 450
+	Mm
		236548 ITB3_MOUSE (1-787): 0: 792: 100.00		SRC_MOUSE (12-442): 7.97e-170: 489: 40.00
+	Hs
		424003 ITB3_HUMAN (1-787): 0: 762: 90.61		SRC_HUMAN (12-442): 3.57e-171: 492: 39.78
+	Rn
		1057712 ITB3_RAT (1-787): 0: 787: 96.19		LYN_RAT (4-445): 4.77e-161: 466: 37.69
+	Mm
		362434 ITB1_MOUSE (10-786): 0: 731: 43.27		ABL1_MOUSE (5-447): 5.64e-166: 498: 38.05
+	Hs
		423995 ITB3_HUMAN (1-787): 0: 762: 90.61		LYN_HUMAN (4-445): 1.63e-160: 464: 37.34
+	Mm
		478492 ITB1_MOUSE (10-786): 0: 731: 43.27		FGR_MOUSE (12-442): 5.89e-166: 478: 37.75
+	Mm
		465766 ITB1_MOUSE (10-786): 0: 731: 43.27		HCK_MOUSE (7-445): 3.94e-163: 471: 36.56
+	Hs
		431659 ITB1_HUMAN (10-786): 0: 725: 43.52		LYN_HUMAN (4-445): 1.63e-160: 464: 37.34
+	Hs
		362118 ITB2_HUMAN (26-785): 0: 645: 38.73		ABL1_HUMAN (5-447): 1.22e-165: 497: 38.05
+	Hs
		424051 ITB2_HUMAN (26-785): 0: 645: 38.73		LYN_HUMAN (4-445): 1.63e-160: 464: 37.34
+	Dm
		262710 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		ABL_DROME (5-447): 2.56e-164: 505: 38.55
+	Hs
		463258 TEN1_HUMAN (362-501): 8.26e-09: 61.6: 9.29		YES_HUMAN (12-442): 8.68e-171: 492: 37.75