HitPredict

Interactor 1: CCNT1 (O60563)
Cyclin-T1 (CycT1) (Cyclin-T)
Gene: CCNT1

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.997

The method score is based on:

Property Details
Experiments 15107825, 27684187, 12944466, 12832472, 12588988, 30652970, 10574912, 9499409, 10958691, 19818711, 17700062, 15546612, 20305087, 15528190, 18566585, 14627702, 9491887, 18483487, 21697490, 26186194 and 34 others

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Identification Methods pull down, affinity chromatography technology, two hybrid, enzymatic study, x-ray crystallography, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_N~Pkinase
Common GO terms GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
and 7 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 726
Hs

1 372
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024