HitPredict

Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29568061
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 646
+	Hs
		236902 BUB1B_HUMAN (1-1050): 0: 826: 100.00		HSP72_HUMAN (2-646): 0: 940: 85.47
+	Hs
		503390 KPCA_HUMAN (576-1044): 3.3e-109: 356: 13.75		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		503528 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		564016 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		504037 KCC2D_HUMAN (764-1021): 2.99e-96: 316: 16.61		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		504975 KCC2A_HUMAN (764-985): 1.69e-60: 216: 17.75		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		160349 AURKA_HUMAN (671-986): 1.25e-38: 151: 16.01		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		160460 AURKA_HUMAN (671-986): 1.25e-38: 151: 16.01		HSP72_HUMAN (2-646): 0: 940: 85.47