HitPredict

Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: 2A5E (Q16537)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)
Gene: PPP2R5E

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23345399
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 467
+	Hs
		236929 BUB1B_HUMAN (1-1050): 0: 826: 100.00		2A5D_HUMAN (4-454): 0: 708: 67.91
+	Hs
		236933 BUB1B_HUMAN (1-1050): 0: 826: 100.00		2A5A_HUMAN (12-434): 0: 705: 80.43
+	Hs
		236934 BUB1B_HUMAN (1-1050): 0: 826: 100.00		2A5B_HUMAN (2-463): 0: 696: 71.92
+	Hs
		236922 BUB1B_HUMAN (1-1050): 0: 826: 100.00		2A5G_HUMAN (38-457): 0: 685: 70.76
+	Dm
		1213388 AKT1_DROME (514-1044): 3.97e-116: 373: 11.81		Q9VB23_DROME (11-463): 0: 704: 75.77
+	Ce
		185206 AKT1_CAEEL (632-1044): 1.61e-107: 347: 13.36		2A51_CAEEL (11-467): 0: 697: 67.40