Interactor 1: CCNT2 (O60583)
Cyclin-T2 (CycT2)
Gene: CCNT2

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 9499409, 16331689, 26186194, 28514442, 27684187, 24981860, 33961781, 35271311, 32707033, 36736316, 17643375, 18566585, 10465067, 21729782, 23602568, 23455922
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_N~Pkinase
Common GO terms GO:0001223 - transcription coactivator binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
and 7 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 730
Hs

1 372
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+ Sp

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Last updated: 15 Jul 2024