HitPredict

Interactor 1: ILK (Q13418)
Scaffold protein ILK (ILK-1) (ILK-2) (Inactive integrin-linked kinase) (p59ILK)
Gene: ILK

Interactor 2: PDLI5 (Q96HC4)
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)
Gene: PDLIM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	GO:0005829 - cytosol GO:0015629 - actin cytoskeleton GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 452 Hs			1 596
+	Ce
		113316 ILKH_CAEEL (1-450): 5.63e-124: 370: 56.44		G5EFG1_CAEEL (1-591): 1.98e-66: 231: 20.41
+	Mm
		237381 ILK_MOUSE (1-452): 2.33e-146: 426: 99.56		PAXI_MOUSE (96-534): 8.61e-37: 146: 14.81
+	Hs
		104037 ILK_HUMAN (1-452): 5.36e-147: 428: 100.00		F5GZ78_HUMAN (96-534): 4.99e-35: 141: 13.90
+	Hs
		878448 ILK_HUMAN (1-452): 5.36e-147: 428: 100.00		PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90
+	Rn
		1226352 ILK_RAT (1-452): 2.33e-146: 426: 99.56		PAXI_RAT (140-534): 2.65e-34: 139: 15.44
+	Hs
		253949 ILK_HUMAN (1-452): 5.36e-147: 428: 100.00		LPXN_HUMAN (164-535): 1.14e-30: 125: 17.20
+	Hs
		1104429 ILK_HUMAN (1-452): 5.36e-147: 428: 100.00		LIMS2_HUMAN (436-576): 6.88e-11: 65.9: 29.45
+	Hs
		870124 ILK_HUMAN (1-452): 5.36e-147: 428: 100.00		LIMS1_HUMAN (436-573): 4.48e-10: 63.2: 29.37
+	Mm
		237386 ILK_MOUSE (1-452): 2.33e-146: 426: 99.56		LIMS1_MOUSE (436-573): 4.65e-10: 63.2: 29.37
+	Hs
		439995 LCK_HUMAN (167-449): 1.45e-109: 334: 21.99		PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90
+	Ce
		895855 ILKH_CAEEL (1-450): 5.63e-124: 370: 56.44		UNC97_CAEEL (419-573): 1.48e-15: 80.1: 30.86
+	Mm
		431364 SRC_MOUSE (173-448): 1.42e-97: 304: 24.21		PAXI_MOUSE (96-534): 8.61e-37: 146: 14.81
+	Hs
		557175 SRC_HUMAN (173-448): 1.45e-98: 307: 24.56		PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90
+	Hs
		463023 YES_HUMAN (176-448): 5.04e-98: 305: 26.60		PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90
+	Hs
		440176 LCK_HUMAN (167-449): 1.45e-109: 334: 21.99		AJUBA_HUMAN (79-533): 7.91e-21: 98.4: 13.86
+	Hs
		117131 J3QRU1_HUMAN (176-448): 5.78e-98: 305: 26.60		PDLI7_HUMAN (257-594): 6.85e-30: 125: 15.68
+	Hs
		463235 YES_HUMAN (176-448): 5.04e-98: 305: 26.60		PDLI7_HUMAN (257-594): 6.85e-30: 125: 15.68
+	Hs
		557321 SRC_HUMAN (173-448): 1.45e-98: 307: 24.56		TRIP6_HUMAN (87-542): 2.33e-28: 120: 14.26
+	Hs
		270702 SRC_HUMAN (173-448): 1.45e-98: 307: 24.56		LDB3_HUMAN (3-426): 2.38e-27: 119: 25.35