Interactor 1: ILK (Q13418)
Scaffold protein ILK (ILK-1) (ILK-2) (Inactive integrin-linked kinase) (p59ILK)
Gene: ILK

Interactor 2: LIMS2 (Q7Z4I7)
LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2)
Gene: LIMS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 12167643, 32707033, 36736316, 23455922
Identification Methods affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~LIM
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 452
Hs

1 341
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+ Rn
+ Mm
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+ Mm
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+ Dm
+ Ce
+ Hs
+ Ce
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+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025