HitPredict

Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 142
+	Hs
		240130 HCN1_HUMAN (1-890): 0: 684: 100.00		AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22
+	Mm
		292119 HCN1_MOUSE (1-890): 0: 651: 90.35		AP2S1_MOUSE (1-142): 6.18e-46: 147: 100.00