Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN
Interactor 2: WRIP1 (Q96S55)
ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1)
Gene: WRNIP1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 1.00 | 0.754 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~ubiquitin, ubiquitin~zf-WRNIP1_ubi |
| Common GO terms | GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0048471 - perinuclear region of cytoplasm |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
