HitPredict

Interactor 1: DIAP2 (O60879)
Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2)
Gene: DIAPH2

Interactor 2: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1101 Hs			1 192
+	Hs
		925658 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		564704 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		545645 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		892621 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		951386 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		894489 DIAP3_HUMAN (13-1093): 0: 886: 56.56		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		900958 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		436532 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		925531 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		545484 FMNL3_HUMAN (91-1091): 0: 642: 21.57		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		894328 FMNL2_HUMAN (91-1091): 0: 651: 22.60		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		900815 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		436466 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		894190 FMNL3_HUMAN (91-1091): 0: 642: 21.57		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		900661 FMNL3_HUMAN (91-1091): 0: 642: 21.57		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Dd
		710114 FORH_DICDI (72-1074): 0: 606: 20.76		RAC1A_DICDI (1-192): 3.12e-81: 241: 78.35
+	Dm
		776921 FRL_DROME (192-1093): 0: 586: 21.41		RAC1_DROME (1-192): 7.95e-82: 242: 89.06
+	Dm
		776944 FRL_DROME (192-1093): 0: 586: 21.41		CDC42_DROME (1-192): 1.03e-76: 229: 69.27
+	Hs
		314838 FMNL1_HUMAN (30-1078): 0: 563: 19.45		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		314853 FMNL1_HUMAN (30-1078): 0: 563: 19.45		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75