HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21231916
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042026 - protein refolding GO:0051082 - unfolded protein binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 643
+	Hs
		243312 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		HS71L_HUMAN (1-643): 0: 960: 79.32
+	Hs
		243275 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		564015 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		564136 DNJA4_HUMAN (4-410): 3.01e-152: 437: 53.17		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		243348 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		HSP72_HUMAN (3-643): 0: 925: 77.45
+	Hs
		681341 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		HS71L_HUMAN (1-643): 0: 960: 79.32
+	Hs
		503527 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		483775 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		HS71B_HUMAN (5-643): 0: 934: 82.16
+	Hs
		681383 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		HSP72_HUMAN (3-643): 0: 925: 77.45
+	Sc
		449929 MAS5_YEAST (4-412): 6.79e-144: 417: 46.73		HSP73_YEAST (8-643): 0: 910: 70.59
+	Hs
		564203 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Sp
		223772 MAS5_SCHPO (4-412): 1.47e-140: 408: 46.97		HSP72_SCHPO (8-613): 0: 907: 73.60
+	Hs
		714049 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		HS71L_HUMAN (1-643): 0: 960: 79.32
+	Hs
		714088 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		HS71L_HUMAN (1-643): 0: 960: 79.32
+	Ce
		220080 O45502_CAEEL (4-411): 2.81e-128: 377: 45.97		HSP1_CAEEL (4-643): 0: 922: 77.07
+	Hs
		504564 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		504901 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		483809 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		HS71B_HUMAN (5-643): 0: 934: 82.16
+	Hs
		871728 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		HSP72_HUMAN (3-643): 0: 925: 77.45
+	Hs
		871816 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		HSP72_HUMAN (3-643): 0: 925: 77.45