HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: CSK22 (P19784)
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
Gene: CSNK2A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31239290, 32416067, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 350
+	Hs
		244265 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36
+	Hs
		243949 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74
+	Hs
		586572 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00
+	Hs
		586761 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00
+	Hs
		631394 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36
+	Hs
		91522 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		E7EU96_HUMAN (1-349): 1.27e-123: 362: 81.13
+	Hs
		934182 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36
+	Sc
		584789 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		CSK22_YEAST (8-326): 2.64e-123: 359: 59.69
+	Hs
		586792 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00
+	At
		1106545 GTE1_ARATH (299-641): 3.23e-35: 141: 17.49		MPK6_ARATH (2-337): 5.11e-120: 353: 24.14
+	Sp
		771122 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		CSK2A_SCHPO (8-326): 1.44e-117: 344: 64.89
+	Sc
		584698 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		CSK22_YEAST (8-326): 2.64e-123: 359: 59.69
+	Sc
		584705 BDF1_YEAST (7-303): 2.12e-26: 118: 17.85		CSK22_YEAST (8-326): 2.64e-123: 359: 59.69
+	Hs
		934363 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36
+	Hs
		625534 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74
+	Hs
		625533 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74
+	Hs
		1082605 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		MK14_HUMAN (18-343): 1.11e-117: 346: 29.38
+	Dm
		437070 Q4V5A7_DROME (322-503): 1.9e-21: 102: 25.68		CSK2A_DROME (7-335): 3.26e-119: 349: 81.46
+	Zm
		75008 K7TPV5_MAIZE (67-252): 2.88e-21: 101: 20.53		B4FG60_MAIZE (23-341): 1.11e-118: 349: 26.28
+	Sc
		550002 BDF1_YEAST (7-303): 2.12e-26: 118: 17.85		CSK21_YEAST (8-331): 9.02e-107: 319: 55.62