HitPredict

Interactor 1: ZN292 (O60281)
Zinc finger protein 292
Gene: ZNF292

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27705803, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2723 Hs			1 183
+	Hs
		244072 ZN292_HUMAN (1-2723): 0: 1942: 98.72		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		244081 ZN292_HUMAN (1-2723): 0: 1942: 98.72		CBX1_HUMAN (36-180): 1.03e-53: 170: 71.33
+	Hs
		216349 ZN292_HUMAN (1-2723): 0: 1942: 98.72		SUV91_HUMAN (3-179): 4.75e-40: 141: 16.20
+	Hs
		67023 ZN729_HUMAN (1947-2689): 3.16e-166: 552: 12.39		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		67018 ZN729_HUMAN (1947-2689): 3.16e-166: 552: 12.39		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		67021 ZN729_HUMAN (1947-2689): 3.16e-166: 552: 12.39		CBX1_HUMAN (36-180): 1.03e-53: 170: 71.33
+	Hs
		70557 ZN850_HUMAN (789-1412): 2.73e-114: 394: 10.61		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		853234 ZN543_HUMAN (450-857): 5.73e-123: 404: 17.43		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		1051147 ZNF91_HUMAN (1712-2171): 1.23e-97: 347: 11.74		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		853307 Z585A_HUMAN (1703-2197): 6.03e-114: 384: 12.40		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		339003 ZN107_HUMAN (781-1416): 4.23e-127: 423: 10.02		CBX6_HUMAN (21-124): 3.32e-27: 107: 27.78
+	Hs
		853287 Z585B_HUMAN (1694-2138): 2.51e-92: 321: 11.27		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		585028 ZN250_HUMAN (592-873): 3.62e-70: 249: 15.39		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1097427 ZN565_HUMAN (508-746): 3.67e-70: 248: 17.41		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		776911 ZNF93_HUMAN (703-1132): 1.07e-68: 247: 15.87		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1097401 ZN227_HUMAN (1700-2060): 9.16e-61: 228: 12.09		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1097442 ZN420_HUMAN (998-1416): 6.47e-59: 219: 10.51		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		853329 ZN227_HUMAN (1700-2060): 9.16e-61: 228: 12.09		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		338997 ZN624_HUMAN (923-1199): 7.94e-65: 241: 9.09		CBX6_HUMAN (21-124): 3.32e-27: 107: 27.78
+	Hs
		129758 ZN546_HUMAN (954-1190): 2.15e-60: 227: 8.13		CBX4_HUMAN (21-121): 4.97e-27: 108: 29.52