HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: TAF3 (Q5VWG9)
Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140)
Gene: TAF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 929
+	Hs
		244466 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PLEC_HUMAN (30-873): 1.38e-72: 265: 10.21
+	Hs
		244438 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56
+	Hs
		244826 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46
+	Hs
		244791 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CHAP1_HUMAN (118-739): 9.43e-30: 128: 11.47
+	Hs
		631460 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00
+	Hs
		1066999 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00
+	Hs
		244571 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NIPBL_HUMAN (274-754): 7.04e-10: 65.4: 16.73
+	Hs
		244681 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		THOC2_HUMAN (339-641): 7.81e-10: 65.4: 20.26
+	Hs
		1139024 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00
+	Hs
		631425 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56
+	Hs
		1056838 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56
+	Hs
		1139022 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00
+	Hs
		631557 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46
+	Hs
		1067107 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46
+	Hs
		1067096 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		CHAP1_HUMAN (118-739): 9.43e-30: 128: 11.47
+	Hs
		1067006 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		NIPBL_HUMAN (274-754): 7.04e-10: 65.4: 16.73
+	Hs
		1067060 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		THOC2_HUMAN (339-641): 7.81e-10: 65.4: 20.26
+	Pf
		1211292 Q8IB67_PLAF7 (141-455): 1.37e-29: 130: 15.64		Q8I2B4_PLAF7 (115-701): 7.77e-12: 71.8: 9.82
+	Dm
		532749 FSH_DROME (320-483): 8.28e-29: 128: 33.13		Q9VLS7_DROME (89-877): 5.22e-10: 65.9: 8.04
+	Dm
		1370354 NU301_DROME (330-457): 2.51e-24: 113: 30.47		Q9VLS7_DROME (89-877): 5.22e-10: 65.9: 8.04