HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32416067, 33567268, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1368
+	Hs
		1067187 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Hs
		1271510 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Hs
		1271465 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		MED23_HUMAN (1-1368): 0: 2164: 100.00