Protein: AQR
RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160)

Gene: AQR
Organism: Homo sapiens
Interactions: 153
UniProt ID: O60306

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003727 - single-stranded RNA binding
GO:0003729 - mRNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

245172

PPIE
Peptidyl-prolyl cis-trans isomerase E

6

2

Small-scale

0.737

High

245148

WDR83
WD repeat domain-containing protein 83

5

9

High-throughput

0.716

High

245171

PRP19
Pre-mRNA-processing factor 19

4

8

High-throughput

0.699

High

245060

RU2A
U2 small nuclear ribonucleoprotein A'

4

3

High-throughput

0.691

High

245102

DHX8
ATP-dependent RNA helicase DHX8

4

4

High-throughput

0.691

High

245082

RUXF
Small nuclear ribonucleoprotein F

3

8

High-throughput

0.675

High

245141

ZN830
Zinc finger protein 830

4

0

Small-scale

0.673

High

245122

ZCH18
Zinc finger CCCH domain-containing protein 18

3

4

High-throughput

0.667

High

245149

YJU2
Splicing factor YJU2

3

1

High-throughput

0.667

High

245126

SNIP1
Smad nuclear-interacting protein 1

4

0

High-throughput

0.664

High

245178

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

4

0

High-throughput

0.664

High

245168

ISY1
Pre-mRNA-splicing factor ISY1 homolog

3

0

Small-scale

0.642

High

245146

USB1
U6 snRNA phosphodiesterase 1

3

0

High-throughput

0.638

High

245049

SYF2
Pre-mRNA-splicing factor SYF2

3

0

High-throughput

0.634

High

222399

PLRG1
Pleiotropic regulator 1

2

9

High-throughput

0.628

High

245064

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

4

High-throughput

0.628

High

245085

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

6

High-throughput

0.628

High

245095

ELAV2
ELAV-like protein 2

2

17

High-throughput

0.628

High

245098

SNW1
SNW domain-containing protein 1

2

2

High-throughput

0.628

High

245158

SYF1
Pre-mRNA-splicing factor SYF1

2

2

Small-scale

0.619

High

245073

IF4A3
Eukaryotic initiation factor 4A-III

2

12

High-throughput

0.611

High

245083

RUXG
Small nuclear ribonucleoprotein G

2

11

High-throughput

0.611

High

245101

RBM39
RNA-binding protein 39

2

14

High-throughput

0.611

High

245139

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

2

10

High-throughput

0.611

High

245081

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.602

High

245156

PININ
Pinin

2

0

High-throughput

0.602

High

245044

SPF27
Pre-mRNA-splicing factor SPF27

2

1

High-throughput

0.601

High

245063

YJU2B
Probable splicing factor YJU2B

2

1

High-throughput

0.601

High

128650

MEN1
Menin

2

2

High-throughput

0.584

High

245104

SUZ12
Polycomb protein SUZ12

2

2

High-throughput

0.584

High

245117

PRP8
Pre-mRNA-processing-splicing factor 8

2

1

High-throughput

0.584

High

245135

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

1

High-throughput

0.574

High

245051

ESR1
Estrogen receptor

2

12

High-throughput

0.571

High

245062

SRC
Proto-oncogene tyrosine-protein kinase Src

2

3

High-throughput

0.571

High

74404

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

16

High-throughput

0.536

High

192525

NUP42
Nucleoporin NUP42

1

2

High-throughput

0.536

High

245036

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

16

High-throughput

0.536

High

245055

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

20

High-throughput

0.536

High

245056

RU2B
U2 small nuclear ribonucleoprotein B''

1

18

High-throughput

0.536

High

245058

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.536

High

245059

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

10

Small-scale

0.536

High

245084

SMD3
Small nuclear ribonucleoprotein Sm D3

1

5

High-throughput

0.536

High

245090

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.536

High

245093

SSRP1
FACT complex subunit SSRP1

1

7

High-throughput

0.536

High

245094

ILF2
Interleukin enhancer-binding factor 2

1

5

High-throughput

0.536

High

245096

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

245099

DX39B
Spliceosome RNA helicase DDX39B

1

9

High-throughput

0.536

High

245105

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.536

High

245106

RNPS1
RNA-binding protein with serine-rich domain 1

1

15

High-throughput

0.536

High

245109

SRSF7
Serine/arginine-rich splicing factor 7

1

20

High-throughput

0.536

High

245110

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

5

High-throughput

0.536

High

245112

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

6

High-throughput

0.536

High

245138

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

245140

PABP5
Polyadenylate-binding protein 5

1

9

High-throughput

0.536

High

245142

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

3

High-throughput

0.536

High

245162

DJC17
DnaJ homolog subfamily C member 17

1

4

High-throughput

0.536

High

245167

RALY
RNA-binding protein Raly

1

11

High-throughput

0.536

High

245175

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

1

High-throughput

0.536

High

245042

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.513

High

245067

LMNB1
Lamin-B1

1

0

High-throughput

0.513

High

245107

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

245123

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.513

High

245129

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

245176

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.513

High

245177

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.513

High

245147

MEP50
Methylosome protein WDR77

1

7

High-throughput

0.508

High

245150

RBM4
RNA-binding protein 4

1

20

High-throughput

0.508

High

245163

RBM22
Pre-mRNA-splicing factor RBM22

1

9

High-throughput

0.508

High

245043

SF3B1
Splicing factor 3B subunit 1

1

3

Small-scale

0.501

High

245037

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.486

High

130316

SPT5H
Transcription elongation factor SPT5

1

4

High-throughput

0.479

High

156742

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

245038

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

245040

MCE1
mRNA-capping enzyme

1

3

High-throughput

0.479

High

245045

UBR5
E3 ubiquitin-protein ligase UBR5

1

6

High-throughput

0.479

High

245047

HERC2
E3 ubiquitin-protein ligase HERC2

1

6

High-throughput

0.479

High

245048

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

14

High-throughput

0.479

High

245050

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

245053

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.479

High

245054

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

245057

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

15

High-throughput

0.479

High

245061

PARP1
Poly [ADP-ribose] polymerase 1

1

9

High-throughput

0.479

High

245065

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

245068

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

245069

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.479

High

245070

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

245071

FUS
RNA-binding protein FUS

1

12

High-throughput

0.479

High

245074

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

245075

CDK8
Cyclin-dependent kinase 8

1

3

High-throughput

0.479

High

245076

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

245077

NCBP2
Nuclear cap-binding protein subunit 2

1

18

High-throughput

0.479

High

245078

MGN
Protein mago nashi homolog

1

1

High-throughput

0.479

High

245079

1433G
14-3-3 protein gamma

1

4

High-throughput

0.479

High

245080

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

245086

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.479

High

245087

H31
Histone H3.1

1

2

High-throughput

0.479

High

245088

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

245089

RED1
Double-stranded RNA-specific editase 1

1

12

High-throughput

0.479

High

245091

RON
Macrophage-stimulating protein receptor

1

2

High-throughput

0.479

High

245097

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

245103

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.479

High

245108

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.479

High

245111

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.479

High

245113

PDCD4
Programmed cell death protein 4

1

1

High-throughput

0.479

High

245120

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

245121

RALYL
RNA-binding Raly-like protein

1

20

High-throughput

0.479

High

245124

SIR6
NAD-dependent protein deacylase sirtuin-6

1

6

High-throughput

0.479

High

245128

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

245131

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.479

High

245132

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

7

High-throughput

0.479

High

245133

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

245134

RBP56
TATA-binding protein-associated factor 2N

1

5

High-throughput

0.479

High

245136

FUBP1
Far upstream element-binding protein 1

1

12

High-throughput

0.479

High

245143

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.479

High

245144

RING2
E3 ubiquitin-protein ligase RING2

1

16

High-throughput

0.479

High

245145

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

245154

XRN2
5'-3' exoribonuclease 2

1

6

High-throughput

0.479

High

245155

ATG5
Autophagy protein 5

1

1

High-throughput

0.479

High

245159

ANLN
Anillin

1

3

High-throughput

0.479

High

245161

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.479

High

245165

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

245170

FZR1
Fizzy-related protein homolog

1

12

High-throughput

0.479

High

245174

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

5

High-throughput

0.479

High

134490

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

222562

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

245046

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.458

High

245072

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

245115

EAPP
E2F-associated phosphoprotein

1

0

High-throughput

0.458

High

245164

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

71544

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

11

High-throughput

0.445

High

245114

NCBP3
Nuclear cap-binding protein subunit 3

1

2

High-throughput

0.445

High

245116

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

245166

DDX41
Probable ATP-dependent RNA helicase DDX41

1

4

High-throughput

0.445

High

245092

1433F
14-3-3 protein eta

1

4

High-throughput

0.437

High

245118

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

245152

RHBT2
Rho-related BTB domain-containing protein 2

1

6

High-throughput

0.437

High

245153

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

5

High-throughput

0.437

High

245157

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

245169

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.437

High

245052

ANGI
Angiogenin

1

0

High-throughput

0.426

High

245100

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

245039

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.407

High

245179

NPTN
Neuroplastin

1

1

High-throughput

0.407

High

245066

CD44
CD44 antigen

2

0

High-throughput

0.328

High

245119

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

245137

K1143
Uncharacterized protein KIAA1143

2

0

High-throughput

0.328

High

245127

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

245160

NPDC1
Neural proliferation differentiation and control protein 1

1

0

High-throughput

0.279

Low

245173

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.279

Low

245041

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

245125

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

245130

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.249

Low

245151

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025