Interactor 1: CATL2 (O60911)
Cathepsin L2 (EC 3.4.22.43) (Cathepsin U) (Cathepsin V)
Gene: CTSV

Interactor 2: CATK (P43235)
Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X)
Gene: CTSK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Inhibitor_I29~Inhibitor_I29, Inhibitor_I29~Peptidase_C1, Peptidase_C1~Peptidase_C1
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006955 - immune response
and 6 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 334
Hs

1 329
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024