HitPredict

Interactor 1: RPN2 (O74762)
26S proteasome regulatory subunit rpn2
Gene: RPN2

Interactor 2: PRS8 (P41836)
26S proteasome regulatory subunit 8 homolog (Protein let1)
Gene: let1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22307589
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0008540 - proteasome regulatory particle, base subcomplex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 965 Sp			1 403
+	At
		221383 PSD1A_ARATH (9-959): 0: 1199: 43.66		PRS4A_ARATH (7-393): 5.26e-135: 395: 45.22
+	At
		1341469 PSD1B_ARATH (9-959): 0: 1176: 42.76		PRS4A_ARATH (7-393): 5.26e-135: 395: 45.22
+	Hs
		906907 PSMD1_HUMAN (11-939): 0: 1140: 43.04		PRS4_HUMAN (9-395): 9.52e-136: 397: 45.48
+	Hs
		798739 PSMD1_HUMAN (11-939): 0: 1140: 43.04		PRS6B_HUMAN (10-396): 9.6e-118: 350: 42.12
+	Hs
		730338 PSMD1_HUMAN (11-939): 0: 1140: 43.04		PRS7_HUMAN (80-388): 2.37e-112: 337: 56.31
+	Dm
		820502 PSMD1_DROME (12-939): 0: 1029: 41.21		PRS4_DROME (7-395): 1.05e-135: 397: 44.22
+	Hs
		693 A0A087WW66_HUMAN (11-939): 0: 1052: 40.85		PRS6B_HUMAN (10-396): 9.6e-118: 350: 42.12
+	Hs
		692 A0A087WW66_HUMAN (11-939): 0: 1052: 40.85		PRS7_HUMAN (80-388): 2.37e-112: 337: 56.31
+	Dm
		1181026 PSMD1_DROME (12-939): 0: 1029: 41.21		Q7KMQ0_DROME (80-388): 3.53e-111: 334: 55.34
+	Sc
		693349 RPN2_YEAST (12-964): 0: 969: 40.92		PRS8_YEAST (6-403): 7.89e-121: 358: 76.38
+	Sc
		693271 RPN2_YEAST (12-964): 0: 969: 40.92		PRS7_YEAST (80-389): 1.94e-109: 331: 55.81
+	Hs
		913340 PSMD1_HUMAN (11-939): 0: 1140: 43.04		PRS10_HUMAN (4-94): 1.14e-10: 64.8: 9.89
+	Hs
		907132 PSMD1_HUMAN (11-939): 0: 1140: 43.04		PRS8_HUMAN (4-111): 1.96e-09: 60.9: 9.26
+	Hs
		701 A0A087WW66_HUMAN (11-939): 0: 1052: 40.85		PRS10_HUMAN (4-94): 1.14e-10: 64.8: 9.89
+	Hs
		700 A0A087WW66_HUMAN (11-939): 0: 1052: 40.85		PRS8_HUMAN (4-111): 1.96e-09: 60.9: 9.26
+	Hs
		66339 PSMD2_HUMAN (18-779): 0: 761: 18.07		A8K2M0_HUMAN (10-396): 9.6e-118: 350: 42.12
+	Hs
		730247 PSMD2_HUMAN (18-779): 0: 761: 18.07		PRS7_HUMAN (80-388): 2.37e-112: 337: 56.31
+	Dm
		1359019 PSMD1_DROME (12-939): 0: 1029: 41.21		Q9W414_DROME (4-94): 1.61e-11: 67.5: 13.19
+	Dm
		186132 PSMD1_DROME (12-939): 0: 1029: 41.21		PRS8_DROME (4-111): 8.06e-10: 62.1: 9.26
+	Dm
		1359001 PSMD1_DROME (12-939): 0: 1029: 41.21		Q9V405_DROME (4-99): 7.8e-09: 59: 10.42