HitPredict

Interactor 1: JAK2 (O60674)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1132 Hs			1 474
+	Hs
		362350 ABL1_HUMAN (837-1126): 3.25e-96: 333: 33.68		MIA2_HUMAN (4-469): 1.28e-30: 128: 12.65
+	Hs
		440616 FYN_HUMAN (800-1125): 1.21e-96: 319: 27.52		TAXB1_HUMAN (59-365): 6.04e-28: 119: 20.46
+	Hs
		440262 LCK_HUMAN (827-1132): 1.51e-97: 321: 30.62		MRCKB_HUMAN (23-351): 3.72e-20: 96.2: 14.57
+	Hs
		463865 LYN_HUMAN (807-1132): 4.35e-93: 309: 30.89		MRCKB_HUMAN (23-351): 3.72e-20: 96.2: 14.57
+	Hs
		117127 J3QRU1_HUMAN (805-1125): 2.55e-97: 322: 27.02		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		463006 YES_HUMAN (805-1125): 2.21e-97: 322: 27.02		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		440414 FYN_HUMAN (800-1125): 1.21e-96: 319: 27.52		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		440112 LCK_HUMAN (827-1132): 1.51e-97: 321: 30.62		MRCKA_HUMAN (44-468): 6.79e-12: 70: 13.40
+	Hs
		557552 SRC_HUMAN (803-1131): 9.13e-99: 325: 25.15		MYH4_HUMAN (15-398): 7.86e-10: 63.5: 10.03
+	Hs
		440658 FYN_HUMAN (800-1125): 1.21e-96: 319: 27.52		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		463377 LYN_HUMAN (807-1132): 4.35e-93: 309: 30.89		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		772682 BLK_HUMAN (795-1124): 4.07e-93: 309: 29.52		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		463575 LYN_HUMAN (807-1132): 4.35e-93: 309: 30.89		MRCKA_HUMAN (44-468): 6.79e-12: 70: 13.40
+	Hs
		463811 LYN_HUMAN (807-1132): 4.35e-93: 309: 30.89		DAPLE_HUMAN (52-339): 4.13e-09: 61.2: 16.88
+	Hs
		411996 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		CCDC6_HUMAN (1-474): 6.19e-48: 173: 100.00
+	Hs
		412194 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		TAXB1_HUMAN (59-365): 6.04e-28: 119: 20.46
+	Hs
		412892 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		MRCKB_HUMAN (23-351): 3.72e-20: 96.2: 14.57
+	Hs
		411474 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		412071 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		MRCKA_HUMAN (44-468): 6.79e-12: 70: 13.40
+	Hs
		411475 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		MYH10_HUMAN (3-329): 8.29e-11: 66.9: 13.46