HitPredict

Interactor 1: IGSF3 (O75054)
Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3)
Gene: IGSF3

Interactor 2: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1194 Hs			1 205
+	Hs
		253673 IGSF3_HUMAN (1-1194): 0: 758: 100.00		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		253648 IGSF3_HUMAN (1-1194): 0: 758: 100.00		RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97
+	Hs
		253645 IGSF3_HUMAN (1-1194): 0: 758: 100.00		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		253636 IGSF3_HUMAN (1-1194): 0: 758: 100.00		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		253638 IGSF3_HUMAN (1-1194): 0: 758: 100.00		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		253622 IGSF3_HUMAN (1-1194): 0: 758: 100.00		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		253635 IGSF3_HUMAN (1-1194): 0: 758: 100.00		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		253642 IGSF3_HUMAN (1-1194): 0: 758: 100.00		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		256062 OBSL1_HUMAN (569-1111): 5.19e-26: 118: 11.36		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		1331019 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		564764 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00
+	Hs
		894044 MYLK_HUMAN (668-1141): 7.03e-22: 105: 12.15		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		915725 SDK2_HUMAN (583-1172): 1.81e-22: 107: 12.14		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		925776 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		894644 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		901110 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		916112 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		530163 NCAM1_HUMAN (33-559): 4.87e-18: 92.2: 13.96		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		436602 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Ce
		104464 UNC89_CAEEL (571-775): 1.82e-09: 64.6: 11.01		G5EBV3_CAEEL (1-204): 1.7e-75: 227: 49.51